Copper-Mediated Diastereoselective C-H Thiolation of Ferrocenes

doi:10.1021/acs.organomet.8b00457

	Copper-Mediated Diastereoselective C-H Thiolation of Ferrocenes
	Kong, Wei-Jun 2; Shao, Qian 2; Li, Ming-Hong 2; Zhou, Zeng-Le 2; Xu, Hui 1; Dai, Hui-Xiong1,2 ; Yu, Jin-Quan 2,3
刊名	ORGANOMETALLICS
	2018-09-10
卷号	37 期号:17 页码:2832-2836
ISSN号	0276-7333
DOI	10.1021/acs.organomet.8b00457
文献子类	Article
英文摘要	The first copper-mediated diastereoselective C-H thiolation of ferrocenes has been developed. A chiral oxazoline directing group with tert-butyl substituent is essential to the high diastereoselectivity ratio and the suppression of overreaction of monothiolated products. This reaction tolerated various functional groups on arylthiols, implying its potential application in N,S-bidentate planar chiral ligands.
资助项目	Shanghai Institute of Materia Medica, Chinese Academy of Sciences[00000000] ; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences[00000000] ; NSFC[21472211] ; NSFC[21502212] ; NSFC[21772211] ; Youth Innovation Promotion Association CAS[2014229] ; Youth Innovation Promotion Association CAS[2018293] ; Institutes for Drug Discovery and Development, Chinese Academy of Sciences[CASIMM 0120163006] ; Science and Technology Commission of Shanghai Municipality[17JC1405000] ; NSF under the CCI Center for Selective C-H Functionalization[CHE-1205646]
WOS关键词	PLANAR-CHIRAL FERROCENES ; ASYMMETRIC-SYNTHESIS ; ENANTIOSELECTIVE SYNTHESIS ; KINETIC RESOLUTION ; STEREOSELECTIVE-SYNTHESIS ; BOND FUNCTIONALIZATION ; SANDWICH COMPOUNDS ; ALLYLIC OXIDATION ; ORTHO-LITHIATION ; DIRECTING GROUP
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000444527200002
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279582]
专题	药物化学研究室
通讯作者	Dai, Hui-Xiong; Yu, Jin-Quan
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, 555 Rd Chong Zhi,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China; 2.Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 20032, Peoples R China; 3.Scripps Res Inst, Dept Chem, 10550 N Torrey Pines Rd, La Jolla, CA 92037 USA
推荐引用方式 GB/T 7714	Kong, Wei-Jun,Shao, Qian,Li, Ming-Hong,et al. Copper-Mediated Diastereoselective C-H Thiolation of Ferrocenes[J]. ORGANOMETALLICS,2018,37(17):2832-2836.
APA	Kong, Wei-Jun.,Shao, Qian.,Li, Ming-Hong.,Zhou, Zeng-Le.,Xu, Hui.,...&Yu, Jin-Quan.(2018).Copper-Mediated Diastereoselective C-H Thiolation of Ferrocenes.ORGANOMETALLICS,37(17),2832-2836.
MLA	Kong, Wei-Jun,et al."Copper-Mediated Diastereoselective C-H Thiolation of Ferrocenes".ORGANOMETALLICS 37.17(2018):2832-2836.