Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine

doi:10.1016/j.tetlet.2013.05.019

	Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine
	Liu, Wenjing 1; Mei, Desheng 3; Wang, Wei 1,2; Duan, Wenhu1,3
刊名	TETRAHEDRON LETTERS
	2013-07-17
卷号	54 期号:29 页码:3791-3793
关键词	Asymmetric conjugate addition Cinchona alkaloids Enones Chiral primary amine catalysis Nitroalkanes
ISSN号	0040-4039
DOI	10.1016/j.tetlet.2013.05.019
文献子类	Article
英文摘要	A cinchona alkaloid derived primary amine catalyzed conjugate addition of nitroalkanes to enones is described. The process affords the Michael adducts in good yield and with up to 99% ee for both acyclic and cyclic enones. (C) 2013 Elsevier Ltd. All rights reserved.
资助项目	Chinese National Natural Science Foundation[81102461] ; Chinese National Natural Science Foundation[81021062] ; Chinese National Natural Science Foundation[90813034] ; Chinese National Programs for High Technology Research and Development[2012AA020302] ; NSF[CHE-1057569]
WOS关键词	ASYMMETRIC MICHAEL ADDITION ; ALPHA,BETA-UNSATURATED KETONES ; PYRROLIDINE SULFONAMIDE ; CYCLIC ENONES ; ORGANOCATALYST ; NITROOLEFINS ; 9-AMINO-9-DEOXYEPIQUININE ; ALDEHYDES ; NITRO
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000324005200016
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277538]
专题	药物化学研究室
通讯作者	Wang, Wei
作者单位	1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China; 2.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA 3.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, Shanghai 201203, Peoples R China;
推荐引用方式 GB/T 7714	Liu, Wenjing,Mei, Desheng,Wang, Wei,et al. Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine[J]. TETRAHEDRON LETTERS,2013,54(29):3791-3793.
APA	Liu, Wenjing,Mei, Desheng,Wang, Wei,&Duan, Wenhu.(2013).Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine.TETRAHEDRON LETTERS,54(29),3791-3793.
MLA	Liu, Wenjing,et al."Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine".TETRAHEDRON LETTERS 54.29(2013):3791-3793.