The synthesis of dendroflorin
Deng, Yi2,4; Jiang, Kun2; Cai, Mao-Jun3; Qu, Shi-Jin2; Dai, Yi-Ru1; Tan, Chang-Heng2
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2017
卷号19期号:6页码:602-609
关键词Total synthesis dendroflorin Suzuki-Miyaura reaction localization effect
ISSN号1028-6020
DOI10.1080/10286020.2017.1324953
文献子类Article
英文摘要The first synthesis of dendroflorin has been achieved in 10 steps with an overall yield of 5.5%. The key step in the synthesis features the biphenyl structure is built through Suzuki-Miyaura reaction. In addition, the ortho-localization effect induced by aromatic substituent during the bromination of intermediate 8 is also observed and discussed.
资助项目"Personalized Medicines - Molecular Signature-based Drug Discovery and Development", Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040315]
WOS关键词N-BROMOSUCCINIMIDE ; BROMINATION
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
出版者TAYLOR & FRANCIS LTD
WOS记录号WOS:000401984100009
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/275717]  
专题天然药物化学研究室
通讯作者Tan, Chang-Heng
作者单位1.Shanghai Univ Engn Sci, Coll Chem & Chem Engn, Shanghai 201620, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Nat Med Chem, Shanghai 201203, Peoples R China;
3.Biorun Pharm Nantong Co Ltd, Nantong 226413, Peoples R China;
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Deng, Yi,Jiang, Kun,Cai, Mao-Jun,et al. The synthesis of dendroflorin[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2017,19(6):602-609.
APA Deng, Yi,Jiang, Kun,Cai, Mao-Jun,Qu, Shi-Jin,Dai, Yi-Ru,&Tan, Chang-Heng.(2017).The synthesis of dendroflorin.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,19(6),602-609.
MLA Deng, Yi,et al."The synthesis of dendroflorin".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 19.6(2017):602-609.
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