Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia

doi:10.1016/j.phytochem.2006.03.005

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	Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia
	Chen, Wenliang ; Tang, Weidong ; Lou, Liguang; Zhao, Weimin
刊名	PHYTOCHEMISTRY
	2006-05
卷号	67 期号:10 页码:1041-1047
关键词	Helicteres angustifolia Sterculiaceae pregnane coumarin triterpenoid cytotoxicity
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2006.03.005
文献子类	Article
英文摘要	2 alpha,7 beta,20 alpha-Trihydroxy-3 beta,21-dimethoxy-5-pregnene (1), 6,7,9 alpha-trihydroxy-3,8, 11 alpha-trimethyleyclohexo-[d,e]-coumarin (2), 3 beta-phy-hydroxy-27-benzoyloxylup-20(29)-en-28-oic acid (3), and 3 beta-hydroxy-27-benzoyloxylup-20(29)-en-28-oic acid methyl ester (4), along with 24 known compounds were isolated and structurally characterized from roots and aerial parts of Helicteres angustifolia (Sterculiaceae). In a preliminary bioassay, the two cucurbitacin derivatives, cucurbitacin D and J exhibited significant inhibitory activities against the growth of both hepatocellular carcinoma BEL-7402 cells and malignant melanoma SK-MEL-28 cells in vitro. (c) 2006 Elsevier Ltd. All rights reserved.
WOS关键词	CUCURBITACINS ; SPECTROSCOPY ; GLYCOSIDES ; FRUITS ; ISORA ; ACID
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000238456200015
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273613]
专题	天然药物化学研究室
通讯作者	Zhao, Weimin
作者单位	1.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Dept Nat Prod Chem, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Chen, Wenliang,Tang, Weidong,Lou, Liguang,et al. Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia[J]. PHYTOCHEMISTRY,2006,67(10):1041-1047.
APA	Chen, Wenliang,Tang, Weidong,Lou, Liguang,&Zhao, Weimin.(2006).Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia.PHYTOCHEMISTRY,67(10),1041-1047.
MLA	Chen, Wenliang,et al."Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia".PHYTOCHEMISTRY 67.10(2006):1041-1047.