Chemistry and bioactivity of secondary metabolites from the soft corals of the genus Sinularia : research advances

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Chemistry and bioactivity of secondary metabolites from the soft corals of the genus Sinularia : research advances
	Liang Linfu; Li Yufen; Liu Haili; Guo Yuewei
刊名	Journal of International Pharmaceutical Research
	2013
卷号	40 期号:6 页码:643-669
关键词	Sinularia secondary metabolite chemical constituents bioactivity
ISSN号	1674-0440
其他题名	短指软珊瑚属次级代谢产物化学成分及其生物活性研究进展
文献子类	Review
英文摘要	Soft corals belong to the genus Sinularia, an important group of marine invertebrates widely distributed in the coral reefs of the world ocean, and offer an enormous source of novel and biologically active compounds. More and more scientists choose them for the research program of marine natural products. As reported, Sinularia furnish a wealth of secondary metabolites, like sesquiterpenes,diterpenes,sesquiterpene-diterpene dimers,diterpene dimers,norsesquiterpenes,norditerpenes,norditerpene dimers, meroterpenes, steroids/steroidal glycosides, ceramides, spermidines, and glycolipids, etc. Particularly interesting, these metabolites found from the title genus animals exhibited a wide range of biological activities ranging from antitumor, antifugal, antiviral to anti-inflammatory activities. This paper reviews the progress in the chemistry and pharmacological activities of the second metabolities from Sinularia during the period from 1975 to April 2013,the aim of which is to provide references for further reaserch on the title genus.
资助项目	国家海洋高技术研究发展计划(863计划)资助项目[00000000] ; 国家自然科学基金资助项目[00000000] ; 中国科学院国家新药研究重点实验室项目[00000000] ; 欧盟第七框架IRSES (2010~2014)资助项目[00000000]
WOS研究方向	General & Internal Medicine (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:5031311
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/269358]
专题	天然药物化学研究室
通讯作者	Guo Yuewei
作者单位	State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式 GB/T 7714	Liang Linfu,Li Yufen,Liu Haili,et al. Chemistry and bioactivity of secondary metabolites from the soft corals of the genus Sinularia : research advances[J]. Journal of International Pharmaceutical Research,2013,40(6):643-669.
APA	Liang Linfu,Li Yufen,Liu Haili,&Guo Yuewei.(2013).Chemistry and bioactivity of secondary metabolites from the soft corals of the genus Sinularia : research advances.Journal of International Pharmaceutical Research,40(6),643-669.
MLA	Liang Linfu,et al."Chemistry and bioactivity of secondary metabolites from the soft corals of the genus Sinularia : research advances".Journal of International Pharmaceutical Research 40.6(2013):643-669.