Investigation on chemical constituents of Spongia officinalis of Weizhou Island

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Investigation on chemical constituents of Spongia officinalis of Weizhou Island
	Sun Dongyu 2; Yao Ligong 1; Han Guanying 3; Guo Yuewei1
刊名	Chinese Journal of Marine Drugs
	2017
卷号	36 期号:4 页码:1-5
关键词	Spongia officinalis chemical constituents C_(21)furanoterpenoids
ISSN号	1002-3461
其他题名	涠洲岛沐浴角骨海绵Spongia officinalis 的化学成分研究
文献子类	Article
英文摘要	Objective To investigate the chemical constituents of Spongia officinalis collected off Weizhou Island,Guangxi Autonomous Region.Methods The compounds were purified by silica gel and Sephadex LH-20column chromatography,followed by semi-preparative HPLC.The structures were identified by NMR and MS approaches as well as comparison with those reported data.Results One sesterterpene, fasciculation(4),together with three C_(21)furanoterpenoids,(-)- untenospongin B(1),kurospongin (2),and C_(21)fasciculatin acid(3),were obtained from the Et_2O extract of the sponge,respectively. Conclusion To data,this was the first investigation on the chemical components of Spongia officinalis off Weizhou Island,leading to the discovery of the four compounds mentioned above from the title animals.In addition,compound 3 was a new natural product.
资助项目	国家自然科学基金项目[00000000] ; 山东省自然科学基金项目[00000000] ; 上海市科委基金项目[00000000] ; 新药研究国家重点实验室项目[00000000]
WOS研究方向	Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:6056253
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/269197]
专题	天然药物化学研究室
通讯作者	Guo Yuewei
作者单位	1.State key laboratory of Drug Research,Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; 2.School of Pharmacy,Jinzhou Medical University, State key laboratory of Drug Research, Jinzhou, Liaoning 121001, China.; 3.School of Pharmacy,Jinzhou Medical University, Jinzhou, Liaoning 121001, China.
推荐引用方式 GB/T 7714	Sun Dongyu,Yao Ligong,Han Guanying,et al. Investigation on chemical constituents of Spongia officinalis of Weizhou Island[J]. Chinese Journal of Marine Drugs,2017,36(4):1-5.
APA	Sun Dongyu,Yao Ligong,Han Guanying,&Guo Yuewei.(2017).Investigation on chemical constituents of Spongia officinalis of Weizhou Island.Chinese Journal of Marine Drugs,36(4),1-5.
MLA	Sun Dongyu,et al."Investigation on chemical constituents of Spongia officinalis of Weizhou Island".Chinese Journal of Marine Drugs 36.4(2017):1-5.