Rhodium-catalyzed Asymmetric Arylation of Nitroalkenes Powered by Simple Chiral Sulfur-Olefin Ligands

doi:10.1002/jccs.201700328

	Rhodium-catalyzed Asymmetric Arylation of Nitroalkenes Powered by Simple Chiral Sulfur-Olefin Ligands
	Wang, Zheng; Chen, Wen-Wen; Xu, Ming-Hua
刊名	JOURNAL OF THE CHINESE CHEMICAL SOCIETY
	2018-03
卷号	65 期号:3 页码:331-336
关键词	Asymmetric catalysis Rhodium Chiral sulfur-olefin ligands Asymmetric arylation Nitroalkenes
ISSN号	0009-4536
DOI	10.1002/jccs.201700328
文献子类	Article; Proceedings Paper
英文摘要	An efficient rhodium-catalyzed enantioselective addition of potassium organotrifluoroborates to nitroalkenes powered by simple chiral sulfur-olefin ligands is reported. This protocol is applicable to a broad range of 2-aryl-, alkyl-, and heteroaryl-substituted nitroalkenes, allowing access to diverse chiral beta, beta-disubstituted nitroethanes in good to excellent yields with high enantioselectivity under mild conditions.
资助项目	National Natural Science Foundation of China[21325209] ; National Natural Science Foundation of China[21472205] ; Shanghai Municipal Committee of Science and Technology (Program of Shanghai Academic Research Leader)[14XD1404400]
WOS关键词	HIGHLY ENANTIOSELECTIVE ARYLATION ; ELECTRON-DEFICIENT OLEFINS ; ARYLBORONIC ACIDS ; CONJUGATE ADDITION ; ORGANOBORONIC ACIDS ; EFFICIENT ACCESS ; BORONIC ACIDS ; PHOSPHITE-OLEFIN ; DIENE LIGANDS ; 1,4-ADDITION
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000428444900006
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279863]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Xu, Ming-Hua
作者单位	Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Wang, Zheng,Chen, Wen-Wen,Xu, Ming-Hua. Rhodium-catalyzed Asymmetric Arylation of Nitroalkenes Powered by Simple Chiral Sulfur-Olefin Ligands[J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY,2018,65(3):331-336.
APA	Wang, Zheng,Chen, Wen-Wen,&Xu, Ming-Hua.(2018).Rhodium-catalyzed Asymmetric Arylation of Nitroalkenes Powered by Simple Chiral Sulfur-Olefin Ligands.JOURNAL OF THE CHINESE CHEMICAL SOCIETY,65(3),331-336.
MLA	Wang, Zheng,et al."Rhodium-catalyzed Asymmetric Arylation of Nitroalkenes Powered by Simple Chiral Sulfur-Olefin Ligands".JOURNAL OF THE CHINESE CHEMICAL SOCIETY 65.3(2018):331-336.