PMes(3)-Promoted Ruthenium-Catalyzed Meta C-H Nitration of 6-Arylpurines

doi:10.1021/acs.joc.8b00149

	PMes(3)-Promoted Ruthenium-Catalyzed Meta C-H Nitration of 6-Arylpurines
	Fan, Zhoulong 2,3,4; Lu, Heng 1; Zhang, Ao1,2,3,4
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2018-03-16
卷号	83 期号:6 页码:3245-3251
ISSN号	0022-3263
DOI	10.1021/acs.joc.8b00149
文献子类	Article
英文摘要	[Graphics] To address the challenge of meta nitration of 6-arylpurine substrates, a versatile ruthenium catalyzed meta C-H nitration is developed. The use of a sterically hindered phosphine ligand is crucial for the catalytic efficiency, and a broad class of 6-arylpurines and nucleosides were found suitable for this process providing corresponding exclusively meta nitrated products in good yields.
资助项目	Chinese NSF[81773565] ; Chinese NSF[81430080] ; National Program on Key Basic Research Project of China[2015CB910603] ; International Cooperative Program[GJHZ1622] ; Key Program of the Frontier Science of the Chinese Academy of Sciences[QYZDJ-SSW-SMC002] ; Shanghai Commission of Science and Technology[16XD1404600]
WOS关键词	BOND ACTIVATION ; REVERSE-TRANSCRIPTASE ; REMOVABLE AUXILIARIES ; SITE-SELECTIVITY ; NATURAL-PRODUCTS ; DIRECTING GROUP ; NUCLEOSIDES ; FUNCTIONALIZATION ; ARENES ; PURINE
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000428002800025
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279847]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Zhang, Ao
作者单位	1.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
推荐引用方式 GB/T 7714	Fan, Zhoulong,Lu, Heng,Zhang, Ao. PMes(3)-Promoted Ruthenium-Catalyzed Meta C-H Nitration of 6-Arylpurines[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(6):3245-3251.
APA	Fan, Zhoulong,Lu, Heng,&Zhang, Ao.(2018).PMes(3)-Promoted Ruthenium-Catalyzed Meta C-H Nitration of 6-Arylpurines.JOURNAL OF ORGANIC CHEMISTRY,83(6),3245-3251.
MLA	Fan, Zhoulong,et al."PMes(3)-Promoted Ruthenium-Catalyzed Meta C-H Nitration of 6-Arylpurines".JOURNAL OF ORGANIC CHEMISTRY 83.6(2018):3245-3251.