Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.
Li, Zhen-Yu1; Xu, Hong-Gui2; Zhao, Zhong-Zhen2; Guo, Yue-Wei1
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2009
卷号11期号:2页码:153-158
关键词Daphniphyllum macropodum Miq alkaloids cytotoxicity
ISSN号1028-6020
DOI10.1080/10286020802618837
文献子类Article
英文摘要Two new Daphniphyllum alkaloids, 4,21-deacetyl-deoxyyuzurimine (1) and macropodumine L (2), together with the two known related alkaloids, have been isolated from the bark of Daphniphyllum macropodum Miq. The structures of the new compounds were elucidated on the basis of the detailed analysis of spectroscopic data, chemical method, and by comparison of the spectroscopic data with those of known compounds. Compounds 2 and 4 exhibited weak cytotoxicity against human carcinoma cell lines SMMC-7721 and HO-8910.
资助项目National Marine '863' projects[2006A A09Z447] ; National Marine '863' Projects[2006AA09Z412] ; National Marine '863' Projects[2007AA09Z447] ; Natural Science Foundation of China[30730108] ; Natural Science Foundation of China[20721003] ; STCSM[07XD14036] ; STCSM[06DZ22028] ; CAS Key Project[KSCX2-YW-R-18]
WOS关键词SKELETONS ; CALYCINUM ; CASCADE
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
出版者TAYLOR & FRANCIS LTD
WOS记录号WOS:000263368000009
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/279388]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Guo, Yue-Wei
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China;
2.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
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Li, Zhen-Yu,Xu, Hong-Gui,Zhao, Zhong-Zhen,et al. Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2009,11(2):153-158.
APA Li, Zhen-Yu,Xu, Hong-Gui,Zhao, Zhong-Zhen,&Guo, Yue-Wei.(2009).Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq..JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,11(2),153-158.
MLA Li, Zhen-Yu,et al."Two new Daphniphyllum alkaloids from Daphniphyllum macropodum Miq.".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 11.2(2009):153-158.
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