Diterpenoids from the Hainan Soft Coral Sinularia parva

doi:10.1002/hlca.200800447

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Diterpenoids from the Hainan Soft Coral Sinularia parva
	Li, Yan 1; Gao, An-Hui 1; Huang, Hui 2; Li, Jia1 ; Mollo, Ernesto 3; Gavagnin, Margherita 3; Cimino, Guido 3; Gu, Yu-Cheng 4; Guo, Yue-Wei1
刊名	HELVETICA CHIMICA ACTA
	2009
卷号	92 期号:7 页码:1341-1348
ISSN号	0018-019X
DOI	10.1002/hlca.200800447
文献子类	Article
英文摘要	Two new cembrane diterpenes, sinulaparvalides A and B (1 and 2, resp.), which contain an intriguing seven-membered lactone moiety, along with the four known related cembranoids 3-6, were isolated from the Hainan soft coral Sinularia parva. The structures of compounds I and 2 were established by spectroscopic methods, mainly on the basis of 2D-NMR techniques, and were confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxic activities of these compounds were tested on human colon carcinoma (HCT-116), human promyelocytic leukemia (HL-60), and human lung carcinoma (A-549) tumor cell lines.
资助项目	National Marine 863 Projects[2006AA09Z447] ; National Marine 863 Projects[2006AA09Z412] ; National Marine 863 Projects[2007AA09Z402] ; Natural Science Foundation of China[30730108] ; Natural Science Foundation of China[20721003] ; Natural Science Foundation of China[20772136] ; STCSM Project[07XD14036] ; Syngenta-SIMM-PhD[00000000] ; CAS[KSCX2-YW-R-18]
WOS关键词	FLEXIBILIS ; CEMBRANOLIDE
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000268622500013
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279376]
专题	天然药物化学研究室中科院受体结构与功能重点实验室信息中心新药研究国家重点实验室药理学第一研究室
通讯作者	Guo, Yue-Wei
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China; 3.CNR, Ist Chim Biomol, I-80078 Naples, Italy; 4.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
推荐引用方式 GB/T 7714	Li, Yan,Gao, An-Hui,Huang, Hui,et al. Diterpenoids from the Hainan Soft Coral Sinularia parva[J]. HELVETICA CHIMICA ACTA,2009,92(7):1341-1348.
APA	Li, Yan.,Gao, An-Hui.,Huang, Hui.,Li, Jia.,Mollo, Ernesto.,...&Guo, Yue-Wei.(2009).Diterpenoids from the Hainan Soft Coral Sinularia parva.HELVETICA CHIMICA ACTA,92(7),1341-1348.
MLA	Li, Yan,et al."Diterpenoids from the Hainan Soft Coral Sinularia parva".HELVETICA CHIMICA ACTA 92.7(2009):1341-1348.