Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O

doi:10.1021/jo802396a

	Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O
	Ye, Deju; Liu, Wenfeng; Zhang, Dengyou; Feng, Enguang; Jiang, Hualiang; Liu, Hong
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2009-02-20
卷号	74 期号:4 页码:1733-1735
ISSN号	0022-3263
DOI	10.1021/jo802396a
文献子类	Article
英文摘要	An efficient approach to the dehydrative sialylation of various substrates with C-4-aminated sialyl-hemiketal donors by using the reagent combination of diphenyl sulfoxide and triflic anhydride is reported. By using a C-4-hindered non-nucleophilic amine auxiliary, excellent yields and high alpha-stereoselectivities were obtained for coupling with a wide range of primary and secondary acceptors.
资助项目	State Key Program of Basic Research of China[2006BAI01B02] ; National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[20472094] ; Shanghai Science and Technology Commission[00000000] ; 863 Hi-Tech Program of China[2006AA020602]
WOS关键词	N-ACETYLNEURAMINIC ACID ; STEREO SELECTIVITY ; O-SIALYLATION ; GLYCOSYLATION ; DERIVATIVES ; 2-O-DEACETYLATION ; THIOGLYCOSIDE ; 4-AMINATION ; ACTIVATION ; GLYCOSIDES
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000263316600040
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/279309]
专题	药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室药物发现与设计中心
通讯作者	Liu, Hong
作者单位	Chinese Acad Sci, Ctr Drug Discovery & Design, Shanghai Inst Mat Med, State Key Lab Drug Res,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Ye, Deju,Liu, Wenfeng,Zhang, Dengyou,et al. Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O[J]. JOURNAL OF ORGANIC CHEMISTRY,2009,74(4):1733-1735.
APA	Ye, Deju,Liu, Wenfeng,Zhang, Dengyou,Feng, Enguang,Jiang, Hualiang,&Liu, Hong.(2009).Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O.JOURNAL OF ORGANIC CHEMISTRY,74(4),1733-1735.
MLA	Ye, Deju,et al."Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O".JOURNAL OF ORGANIC CHEMISTRY 74.4(2009):1733-1735.