Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O | |
Ye, Deju; Liu, Wenfeng; Zhang, Dengyou; Feng, Enguang; Jiang, Hualiang![]() ![]() | |
刊名 | JOURNAL OF ORGANIC CHEMISTRY
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2009-02-20 | |
卷号 | 74期号:4页码:1733-1735 |
ISSN号 | 0022-3263 |
DOI | 10.1021/jo802396a |
文献子类 | Article |
英文摘要 | An efficient approach to the dehydrative sialylation of various substrates with C-4-aminated sialyl-hemiketal donors by using the reagent combination of diphenyl sulfoxide and triflic anhydride is reported. By using a C-4-hindered non-nucleophilic amine auxiliary, excellent yields and high alpha-stereoselectivities were obtained for coupling with a wide range of primary and secondary acceptors. |
资助项目 | State Key Program of Basic Research of China[2006BAI01B02] ; National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[20472094] ; Shanghai Science and Technology Commission[00000000] ; 863 Hi-Tech Program of China[2006AA020602] |
WOS关键词 | N-ACETYLNEURAMINIC ACID ; STEREO SELECTIVITY ; O-SIALYLATION ; GLYCOSYLATION ; DERIVATIVES ; 2-O-DEACETYLATION ; THIOGLYCOSIDE ; 4-AMINATION ; ACTIVATION ; GLYCOSIDES |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | AMER CHEMICAL SOC |
WOS记录号 | WOS:000263316600040 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/279309] ![]() |
专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物发现与设计中心 |
通讯作者 | Liu, Hong |
作者单位 | Chinese Acad Sci, Ctr Drug Discovery & Design, Shanghai Inst Mat Med, State Key Lab Drug Res,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Ye, Deju,Liu, Wenfeng,Zhang, Dengyou,et al. Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O[J]. JOURNAL OF ORGANIC CHEMISTRY,2009,74(4):1733-1735. |
APA | Ye, Deju,Liu, Wenfeng,Zhang, Dengyou,Feng, Enguang,Jiang, Hualiang,&Liu, Hong.(2009).Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O.JOURNAL OF ORGANIC CHEMISTRY,74(4),1733-1735. |
MLA | Ye, Deju,et al."Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-Hemiketal Donors with Ph2SO/Tf2O".JOURNAL OF ORGANIC CHEMISTRY 74.4(2009):1733-1735. |
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