Cytotoxic triterpenoids from Ganoderma lucidum

doi:10.1016/j.phytochem.2010.06.005

	Cytotoxic triterpenoids from Ganoderma lucidum
	Cheng, Chun-Ru; Yue, Qing-Xi; Wu, Zhi-Yuan; Song, Xiao-Yi; Tao, Si-Jia; Wu, Xiao-Hui; Xu, Ping-Ping; Liu, Xuan; Guan, Shu-Hong; Guo, De-An
刊名	PHYTOCHEMISTRY
	2010-09
卷号	71 期号:13 页码:1579-1585
关键词	Ganoderma lucidum Triterpenoids Cytotoxicity Structure and activity relationship
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2010.06.005
文献子类	Article
英文摘要	A systematic study of the metabolites in Ganoderma lucidum led to isolation of 43 triterpenoids, six of them (1-6) are hitherto unknown. The structures of the latter were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. All of the compounds were assayed for their inhibitory activities against human HeLa cervical cancer cell lines. Some compounds exhibit significant cytotoxicity, and their structure-activity relationships are discussed. (C) 2010 Elsevier Ltd. All rights reserved.
资助项目	National Natural Science Foundation of China (NNSFC)[30701077] ; ministry of Sciences and Technology of China[2006BAI08B03-03] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09308-005] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09311-001] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09502-020] ; Ministry of Science and Technology of the People's Republic of China[00000000]
WOS关键词	TUMOR-CELL-LINES ; FR KARST ; ACID-F ; INHIBITORY TRITERPENES ; GANOLUCIDIC ACID ; CONSTITUENTS ; LANOSTANOIDS ; TERPENOIDS ; METABOLITES ; BITTERNESS
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000280983200018
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/278793]
专题	成果转移转化处上海中药现代化研究中心
通讯作者	Guan, Shu-Hong
作者单位	Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Chun-Ru,Yue, Qing-Xi,Wu, Zhi-Yuan,et al. Cytotoxic triterpenoids from Ganoderma lucidum[J]. PHYTOCHEMISTRY,2010,71(13):1579-1585.
APA	Cheng, Chun-Ru.,Yue, Qing-Xi.,Wu, Zhi-Yuan.,Song, Xiao-Yi.,Tao, Si-Jia.,...&Guo, De-An.(2010).Cytotoxic triterpenoids from Ganoderma lucidum.PHYTOCHEMISTRY,71(13),1579-1585.
MLA	Cheng, Chun-Ru,et al."Cytotoxic triterpenoids from Ganoderma lucidum".PHYTOCHEMISTRY 71.13(2010):1579-1585.