Research progress in small molecule IDO-1 inhibitors

	Research progress in small molecule IDO-1 inhibitors
	Zhou Yinghong
刊名	Chinese Journal of Antibiotics
	2016
卷号	41 期号:10 页码:721-726
关键词	IDO-1 IDO-1 Cancer immunotherapy Tryptophan Immune escape
ISSN号	1001-8689
其他题名	小分子IDO-1抑制剂研究进展
文献子类	Review
英文摘要	The interactions between neoplasm and the host immune system are complex and dynamic. Scientists are trying to find out the mechanisms of their interactions and hoping to improve the status of tumor therapy. Correspondingly, Cancer immunotherapy has become a popular research area of Pharmaceutical Industry. Amongst the numerous mediators contributing to cancer-immunity cycle, the enzyme indoleamine 2,3-dioxygenase-1 (IDO-1) has recently attracted special attention. In this article we reviewed advance of IDO-1 from the aspects of physiological function, abnormalities in tumor tissues and drug development status.
WOS研究方向	Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:5830497
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/269231]
专题	信息中心
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式 GB/T 7714	Zhou Yinghong. Research progress in small molecule IDO-1 inhibitors[J]. Chinese Journal of Antibiotics,2016,41(10):721-726.
APA	Zhou Yinghong.(2016).Research progress in small molecule IDO-1 inhibitors.Chinese Journal of Antibiotics,41(10),721-726.
MLA	Zhou Yinghong."Research progress in small molecule IDO-1 inhibitors".Chinese Journal of Antibiotics 41.10(2016):721-726.