Simple and Efficient Copper(I)-Catalyzed Access to Three Versatile Aminocoumarin-Based Scaffolds using Isocyanoacetate
Meng, Tao1; Zou, Yiquan1; Khorev, Oleg2; Jin, Yu1; Zhou, Huayong1; Zhang, Yongliang1; Hu, Dingyu1; Ma, Lanping1; Wang, Xin1; Shen, Jingkang1
刊名ADVANCED SYNTHESIS & CATALYSIS
2011-04-18
卷号353期号:6页码:918-924
关键词3-aminocoumarin chromeno[3,4-d]imidazol-4(1H)-ones copper(I)-catalyzed heterocycle formation ethyl isocyanoacetate 3-substituted methylidene-aminocoumarins
ISSN号1615-4150
DOI10.1002/adsc.201000895
文献子类Article
英文摘要An efficient method has been developed for the one-pot copper(I)-catalyzed synthesis of 3-aminocoumarin and its derivatives, such as 3-substituted methylideneaminocoumarins and chromeno[3,4-d]imidazol-4(1H)-ones. Significantly, the strategy presents a straightforward and efficient approach to constructing biologically useful molecular scaffolds.
资助项目National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09301-001] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09501-010] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09103-074] ; 863 Hi-Tech Research and Development Program, 863 Program of China[2007AA02Z308] ; National Natural Science Foundation of China[81001355]
WOS关键词MULTICOMPONENT REACTIONS ; COMBINATORIAL SYNTHESIS ; 3-COMPONENT CONDENSATION ; DRUG DISCOVERY ; NOVOBIOCIN ; COUMARINS ; PYRAZINES ; CHEMISTRY ; LIBRARY ; ANALOGS
WOS研究方向Chemistry
语种英语
出版者WILEY-V C H VERLAG GMBH
WOS记录号WOS:000290613800019
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/278554]  
专题药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Shen, Jingkang
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
2.Univ Bern, Inselspital, Div Nephrol & Hypertens, CH-3010 Bern, Switzerland
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GB/T 7714
Meng, Tao,Zou, Yiquan,Khorev, Oleg,et al. Simple and Efficient Copper(I)-Catalyzed Access to Three Versatile Aminocoumarin-Based Scaffolds using Isocyanoacetate[J]. ADVANCED SYNTHESIS & CATALYSIS,2011,353(6):918-924.
APA Meng, Tao.,Zou, Yiquan.,Khorev, Oleg.,Jin, Yu.,Zhou, Huayong.,...&Shen, Jingkang.(2011).Simple and Efficient Copper(I)-Catalyzed Access to Three Versatile Aminocoumarin-Based Scaffolds using Isocyanoacetate.ADVANCED SYNTHESIS & CATALYSIS,353(6),918-924.
MLA Meng, Tao,et al."Simple and Efficient Copper(I)-Catalyzed Access to Three Versatile Aminocoumarin-Based Scaffolds using Isocyanoacetate".ADVANCED SYNTHESIS & CATALYSIS 353.6(2011):918-924.
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