Bicunningines A and B, Two New Dimeric Diterpenes from Cunninghamia lanceolata | |
Hou, Xian-Feng1,2; Yao, Sheng1,2![]() ![]() ![]() ![]() | |
刊名 | ORGANIC LETTERS
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2012-01-20 | |
卷号 | 14期号:2页码:460-463 |
ISSN号 | 1523-7060 |
DOI | 10.1021/ol202915r |
文献子类 | Article |
英文摘要 | Two unprecedented dimeric diterpenoids, with a 2,3-dihydrofuran ring fusing an abietane and a 4,5-seco-abietane diterpene, were isolated from Cunninghamia lanceolate. Their structures were elucidated by spectroscopic measurements, and their absolute configurations were determined by quantum chemical TDDFT ECD calculations, chemical transformations, and Mosher's method. The Mosher method carried out with MPA and MTPA esters of the sterically hindered sec-hydroxyl group gave contradictory results, while MPA afforded the correct absolute configuration. |
资助项目 | National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2009ZX09301-001] ; National Natural Science Funds for Distinguished Young Scholar[30925043] ; Ministry of Science and Technology[2010DFA30980] |
WOS关键词 | ABSOLUTE-CONFIGURATION ; CRYPTOMERIA-JAPONICA ; HEARTWOOD ; ABIETANE ; LIGNANS ; ROOTS |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | AMER CHEMICAL SOC |
WOS记录号 | WOS:000299238600009 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/278212] ![]() |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Ye, Yang |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, SIMM CUHK Joint Res Lab Promoting Globlizat Tradi, Shanghai 201203, Peoples R China; 3.Univ Debrecen, Dept Organ Chem, H-4010 Debrecen, Hungary |
推荐引用方式 GB/T 7714 | Hou, Xian-Feng,Yao, Sheng,Mandi, Attila,et al. Bicunningines A and B, Two New Dimeric Diterpenes from Cunninghamia lanceolata[J]. ORGANIC LETTERS,2012,14(2):460-463. |
APA | Hou, Xian-Feng.,Yao, Sheng.,Mandi, Attila.,Kurtan, Tibor.,Tang, Chun-Ping.,...&Ye, Yang.(2012).Bicunningines A and B, Two New Dimeric Diterpenes from Cunninghamia lanceolata.ORGANIC LETTERS,14(2),460-463. |
MLA | Hou, Xian-Feng,et al."Bicunningines A and B, Two New Dimeric Diterpenes from Cunninghamia lanceolata".ORGANIC LETTERS 14.2(2012):460-463. |
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