Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2

doi:10.1021/jm501230c

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	Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2
	Kong, Xiangqian 1; Chen, Limin 1; Jiao, Lianying 2; Jiang, Xiangrui1 ; Lian, Fulin 1; Lu, Junyan 1; Zhu, Kongkai 1; Du, Daohai 1; Liu, Jingqiu 1; Ding, Hong1
刊名	JOURNAL OF MEDICINAL CHEMISTRY
	2014-11-27
卷号	57 期号:22 页码:9512-9521
ISSN号	0022-2623
DOI	10.1021/jm501230c
文献子类	Article
资助项目	Computer Network Information Center, Chinese Academy of Sciences[00000000] ; Shanghai Supercomputing Center[00000000] ; Hi-Tech Research and Development Program of China[2012AA020302] ; National Natural Science Foundation of China[21210003] ; National Natural Science Foundation of China[81230076] ; National Natural Science Foundation of China[91229204] ; National Natural Science Foundation of China[21272246] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program"[2014ZX09507002] ; Chinese Academy of Sciences[00000000] ; Welch Foundation[I-1790]
WOS关键词	PROTEIN-PROTEIN INTERACTIONS ; SMALL-MOLECULE INHIBITORS ; RESISTANT PROSTATE-CANCER ; H3 LYSINE-27 METHYLATION ; MIXED-LINEAGE LEUKEMIA ; STRUCTURE-BASED DESIGN ; RNA-POLYMERASE-II ; METHYLTRANSFERASE ACTIVITY ; HISTONE METHYLATION ; FLUORESCENCE POLARIZATION
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000345722200021
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276825]
专题	药物发现与设计中心中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Luo, Cheng
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Univ Texas SW Med Ctr Dallas, Cecil H & Ida Green Ctr Reprod Biol Sci, Dallas, TX 75390 USA
推荐引用方式 GB/T 7714	Kong, Xiangqian,Chen, Limin,Jiao, Lianying,et al. Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2[J]. JOURNAL OF MEDICINAL CHEMISTRY,2014,57(22):9512-9521.
APA	Kong, Xiangqian.,Chen, Limin.,Jiao, Lianying.,Jiang, Xiangrui.,Lian, Fulin.,...&Luo, Cheng.(2014).Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2.JOURNAL OF MEDICINAL CHEMISTRY,57(22),9512-9521.
MLA	Kong, Xiangqian,et al."Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2".JOURNAL OF MEDICINAL CHEMISTRY 57.22(2014):9512-9521.