Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives | |
Jiang, Min1; Xiang, Haoyue2; Zhu, Fangxia1; Xu, Xing1; Deng, Lianfu1; Yang, Chunhao2![]() | |
刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
![]() |
2015 | |
卷号 | 13期号:40页码:10122-10126 |
ISSN号 | 1477-0520 |
DOI | 10.1039/c5ob01642h |
文献子类 | Article |
英文摘要 | An efficient and practical one-pot domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives from readily available 2-(2-bromophenyl)acetonitriles was developed. The overall protocol involves a Buchwald-Hartwig type coupling and a base-promoted intramolecular nucleophilic reaction. The reaction scope, advantages and limitations are discussed. |
资助项目 | Shanghai Municipal Health Bureau young scientific research project[20144Y0055] ; Shanghai Committee of Science and Technology, China[14ZR1437500] ; Shanghai Committee of Science and Technology, China[13431900702] ; NSFC[81502902] ; NSFC[81321092] ; SKLDR/SIMM[SIMM1403ZZ-01] |
WOS关键词 | ONE-POT SYNTHESIS ; ACCESS ; INDOLE ; ALPHA ; INDOLMYCIN ; INHIBITORS ; CHEMISTRY ; ARYLATION ; DIVERSE ; ANALOGS |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000362729600005 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/276702] ![]() |
专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Deng, Lianfu |
作者单位 | 1.Shanghai Jiao Tong Univ, Sch Med, Shanghai Ruijin Hosp, Shanghai Inst Traumatol & Orthopaed,Shanghai Key, Shanghai 200025, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Jiang, Min,Xiang, Haoyue,Zhu, Fangxia,et al. Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2015,13(40):10122-10126. |
APA | Jiang, Min,Xiang, Haoyue,Zhu, Fangxia,Xu, Xing,Deng, Lianfu,&Yang, Chunhao.(2015).Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives.ORGANIC & BIOMOLECULAR CHEMISTRY,13(40),10122-10126. |
MLA | Jiang, Min,et al."Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives".ORGANIC & BIOMOLECULAR CHEMISTRY 13.40(2015):10122-10126. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论