New Isoprenylated Phenolic Compounds from Morus laevigata
Wang, Meng1; Yu, Bang-Wei2; Yu, Mei-Hua1; Gao, Li-Xin2; Li, Jing-Ya2; Wang, He-Yao2; Li, Jia2; Hou, Ai-Jun1
刊名CHEMISTRY & BIODIVERSITY
2015-06
卷号12期号:6页码:937-945
ISSN号1612-1872
DOI10.1002/cbdv.201400210
文献子类Article
英文摘要Two new isoprenylated flavonoids, laevigasinsAand B (1 and 2, resp.), and one new isoprenylated 2-arylbenzofuran, leavigasin C (3), together with eight known compounds, 4-11, were isolated from the twigs of Morus laevigata. Their structures were elucidated by spectroscopic methods. Laevigasin A (1) showed significant inhibitory effect on alpha-glucosidase in vitro. Notabilisin E (5), taxifolin (10), and hultenin (11) inhibited PTP1B phosphatase activity in vitro.
资助项目National Natural Science Foundation of China[81222045] ; National Natural Science Foundation of China[81125023] ; National Natural Science Foundation of China[21072035] ; Science and Technology Commission of Shanghai Municipality[11431920101] ; Shanghai Municipal Education Commission[12SG02] ; Shanghai Education Development Foundation[12SG02]
WOS关键词ADIPOGENESIS-PROMOTING CONSTITUENTS ; ALPHA-GLUCOSIDASE INHIBITOR ; TYROSINE-PHOSPHATASE 1B ; ALDER-TYPE ADDUCTS ; FLAVONOIDS ; ANTIOXIDANT ; PAKISTAN ; PROTEIN ; PLANTS ; ACIDS
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
语种英语
出版者WILEY-V C H VERLAG GMBH
WOS记录号WOS:000356425500005
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/276506]  
专题国家新药筛选中心
中科院受体结构与功能重点实验室
新药研究国家重点实验室
药理学第三研究室
药物安全性评价中心
通讯作者Hou, Ai-Jun
作者单位1.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714
Wang, Meng,Yu, Bang-Wei,Yu, Mei-Hua,et al. New Isoprenylated Phenolic Compounds from Morus laevigata[J]. CHEMISTRY & BIODIVERSITY,2015,12(6):937-945.
APA Wang, Meng.,Yu, Bang-Wei.,Yu, Mei-Hua.,Gao, Li-Xin.,Li, Jing-Ya.,...&Hou, Ai-Jun.(2015).New Isoprenylated Phenolic Compounds from Morus laevigata.CHEMISTRY & BIODIVERSITY,12(6),937-945.
MLA Wang, Meng,et al."New Isoprenylated Phenolic Compounds from Morus laevigata".CHEMISTRY & BIODIVERSITY 12.6(2015):937-945.
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