Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment

doi:10.7150/thno.15217

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 药物制剂研究中心

	Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment
	Zhang, Pengcheng1,2 ; Hu, Chunhua 1,2,3; Ran, Wei 1,2,4; Meng, Jia 1,2,4; Yin, Qi1,2 ; Li, Yaping1,2
刊名	THERANOSTICS
	2016
卷号	6 期号:7 页码:948-968
关键词	Nanoparticle theranostics imaging photodynamic photothermal
ISSN号	1838-7640
DOI	10.7150/thno.15217
文献子类	Review
英文摘要	Treatments of high specificity are desirable for cancer therapy. Light-triggered nanotheranostics (LTN) mediated cancer therapy could be one such treatment, as they make it possible to visualize and treat the tumor specifically in a light-controlled manner with a single injection. Because of their great potential in cancer therapy, many novel and powerful LTNs have been developed, and are mainly prepared from photosensitizers (PSs) ranging from small organic dyes such as porphyrin-and cyanine-based dyes, semiconducting polymers, to inorganic nanomaterials such as gold nanoparticles, transition metal chalcogenides, carbon nanotubes and graphene. Using LTNs and localized irradiation in combination, complete tumor ablation could be achieved in tumor-bearing animal models without causing significant toxicity. Given their great advances and promising future, we herein review LTNs that have been tested in vivo with a highlight on progress that has been made in the past a couple of years. The current challenges faced by these LTNs are also briefly discussed.
资助项目	National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[81270047] ; National Basic Research Program of China[2012CB932502] ; National Basic Research Program of China[2013CB932503] ; Shanghai Pujiang Program[15PJ1409900]
WOS关键词	GUIDED PHOTOTHERMAL THERAPY ; NEAR-INFRARED LIGHT ; COPPER SULFIDE NANOPARTICLES ; UP-CONVERSION NANOPARTICLES ; WALLED CARBON NANOTUBES ; REDUCED GRAPHENE OXIDE ; TARGETED PHOTODYNAMIC THERAPY ; AGGREGATION-INDUCED EMISSION ; GOLD NANOROD VESICLES ; HUMAN SERUM-ALBUMIN
WOS研究方向	Research & Experimental Medicine
语种	英语
出版者	IVYSPRING INT PUBL
WOS记录号	WOS:000377799600004
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276225]
专题	药物制剂研究中心中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Li, Yaping
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, 501 Haike Rd, Shanghai 201203, Peoples R China; 3.Univ Sci & Technol China, Nano Sci & Technol Inst, Suzhou 215123, Peoples R China; 4.UCAS, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Pengcheng,Hu, Chunhua,Ran, Wei,et al. Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment[J]. THERANOSTICS,2016,6(7):948-968.
APA	Zhang, Pengcheng,Hu, Chunhua,Ran, Wei,Meng, Jia,Yin, Qi,&Li, Yaping.(2016).Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment.THERANOSTICS,6(7),948-968.
MLA	Zhang, Pengcheng,et al."Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment".THERANOSTICS 6.7(2016):948-968.