Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii

doi:10.1016/j.tetlet.2016.06.050

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	Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii
	Meng, Wei-Jia 1; Xiong, Juan 1; Wang, Wen-Xuan 1; Zhang, Hai-Yan2 ; Zeng, Huaqiang 3; Hu, Jin-Feng 1
刊名	TETRAHEDRON LETTERS
	2016-07-20
卷号	57 期号:29 页码:3218-3221
关键词	Phlefargesiine A Lycopodium alkaloid Huperziaceae Phlegmariurus fargesii
ISSN号	0040-4039
DOI	10.1016/j.tetlet.2016.06.050
文献子类	Article
英文摘要	A novel C16N2 Lycopodium alkaloid, phlefargesiine A (1), was isolated from the whole plant of the club moss Phlegmariurus fargesii. The structure and absolute configuration were determined by extensive spectroscopic and computational methods. Compound 1 possesses an unprecedented [6/7/6/6]-tetra cyclic framework, of which the seven-membered ring (ring B) is constructed through a hitherto unknown C-4-C-14 linkage. (C) 2016 Elsevier Ltd. All rights reserved.
资助项目	NSFC[21472021] ; NSFC[81273401] ; NSFC[81202420] ; Ph.D. Programs Foundation of Ministry of Education (MOE) of China[20120071120049] ; National Basic Research Program of China (973 Program)[2013CB530700]
WOS关键词	HUPERZINE-A
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000379630500040
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/275950]
专题	药理学第二研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Xiong, Juan; Hu, Jin-Feng
作者单位	1.Fudan Univ, Sch Pharm, Dept Nat Prod Chem, 826 Zhangheng Rd, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; 3.Inst Bioengn & Nanotechnol, 31 Biopolis Way, The Nanos 138669, Philippines
推荐引用方式 GB/T 7714	Meng, Wei-Jia,Xiong, Juan,Wang, Wen-Xuan,et al. Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii[J]. TETRAHEDRON LETTERS,2016,57(29):3218-3221.
APA	Meng, Wei-Jia,Xiong, Juan,Wang, Wen-Xuan,Zhang, Hai-Yan,Zeng, Huaqiang,&Hu, Jin-Feng.(2016).Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii.TETRAHEDRON LETTERS,57(29),3218-3221.
MLA	Meng, Wei-Jia,et al."Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii".TETRAHEDRON LETTERS 57.29(2016):3218-3221.