Stereoselective synthesis of syn- and anti-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic acid

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Stereoselective synthesis of syn- and anti-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic acid
	Yang, XY; Haug, C; Yang, YP; He, ZS; Ye, Y
刊名	CHINESE CHEMICAL LETTERS
	2003-02
卷号	14 期号:2 页码:130-132
关键词	oxidative ring formation stereoselective synthesis sodium naphthalenide
ISSN号	1001-8417
文献子类	Article
英文摘要	The structure of syn- and anti-N-b-(p-toluenesulfonyl)-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydro pyrrolo[2,3-b] indole-2-carboxylic t-butyl ester was stereoselectively synthesized by oxidative ring formation of N-b-(p-toluenesulfonyl)-L-tryptophan t-butyl ester in methylene chloride containing dimethyldioxirane (DMDO), the p-toluenesulfonyl group and t-butyl group can be easily removed by sodium naphthalenide and trifuoroacetic acid, respectively.
WOS研究方向	Chemistry
语种	英语
出版者	CHINESE CHEMICAL SOCIETY
WOS记录号	WOS:000181228600007
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/274268]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Ye, Y
作者单位	Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, State Key Lab Drug Res, Shanghai 200031, Peoples R China
推荐引用方式 GB/T 7714	Yang, XY,Haug, C,Yang, YP,et al. Stereoselective synthesis of syn- and anti-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic acid[J]. CHINESE CHEMICAL LETTERS,2003,14(2):130-132.
APA	Yang, XY,Haug, C,Yang, YP,He, ZS,&Ye, Y.(2003).Stereoselective synthesis of syn- and anti-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic acid.CHINESE CHEMICAL LETTERS,14(2),130-132.
MLA	Yang, XY,et al."Stereoselective synthesis of syn- and anti-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic acid".CHINESE CHEMICAL LETTERS 14.2(2003):130-132.