Macropodumines A-C: Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq.

doi:10.1002/chem.200600056

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	Macropodumines A-C: Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq.
	Zhang, Wen ; Guo, Yue-Wei; Krohn, Karsten
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2006-06-23
卷号	12 期号:19 页码:5122-5127
关键词	alkaloids macropodumines natural products structure elucidation zwitterions
ISSN号	0947-6539
DOI	10.1002/chem.200600056
文献子类	Article
英文摘要	Three novel alkaloids, mac-ropodurnines A-C (1-3), were isolated from the stem of Daphniphyllum macropodum Miq. Interestingly, the structure of macropodurnine A (1) was characterized as having a fused pentacyclic system including an unusual eleven-membered macrolactone ring, whereas macropodurnine B (2) contains a rare cyclopentadienyl carbanion, which is stabilized as a zwitterion by an internal iminium cation. The structures of these new metabolites were established on the basis of their detailed spectroscopic analysis. In particular, the unique structure of zwitterion 2 was further confirmed by using single-crystal X-ray diffraction analysis.
WOS关键词	METHYL HOMOSECODAPHNIPHYLLATE ; CHEMICAL-SHIFTS ; CALYCINUM ; OLDHAMI ; SECODAPHNIPHYLLINE ; HYDROCARBONS ; GLAUCESCENS ; PAXIANUM
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000238723200018
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273562]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Guo, Yue-Wei
作者单位	1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Univ Paderborn, Dept Chem, D-33098 Paderborn, Germany
推荐引用方式 GB/T 7714	Zhang, Wen,Guo, Yue-Wei,Krohn, Karsten. Macropodumines A-C: Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq.[J]. CHEMISTRY-A EUROPEAN JOURNAL,2006,12(19):5122-5127.
APA	Zhang, Wen,Guo, Yue-Wei,&Krohn, Karsten.(2006).Macropodumines A-C: Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq..CHEMISTRY-A EUROPEAN JOURNAL,12(19),5122-5127.
MLA	Zhang, Wen,et al."Macropodumines A-C: Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq.".CHEMISTRY-A EUROPEAN JOURNAL 12.19(2006):5122-5127.