Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities

doi:10.1007/s11101-016-9472-2

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 天然药物化学研究室

	Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities
	Bao, Han 1; Zhang, Qingwen 1; Ye, Yang2 ; Lin, Ligen 1
刊名	PHYTOCHEMISTRY REVIEWS
	2017-04
卷号	16 期号:2 页码:235-270
关键词	Furanoditerpenoids Distribution Phytochemistry Biological properties
ISSN号	1568-7767
DOI	10.1007/s11101-016-9472-2
文献子类	Review
英文摘要	Furanoditerpenoids are a special group of diterpenoids composing of one or more furan rings, which are rarely found in nature. This review aims to survey the various naturally occurring furanoditerpenoids and their pharmacological activities. A fairly large number of furanoditerpenoids have been reported from the families Euphorbiaceae, Fabaceae and Lamiaceae, and a few ones from the families Asteraceae, Codoniaceae, Dioscoreaceae, Fossombroniaceae, Jamesoniellaceae, Meliaceae, Menispermaceae, Olacaceae, Psathyrellaceae, Sapindaceae and Scapaniaceae. Their distribution correlates strongly with the taxonomic divisions. Most of these plants are widely used in traditional medicines, and furanoditerpenoids have therefore been disclosed with a wide range of bioactivities including anti-cancer, anti-inflammation and anti-microorganism. To structure this review, the furanoditerpenoids were classified into seven types, including clerodane-type (Type I), labdane-type (Type II), cassane-type (Type III), abietane-type (Type IV), spongian-type (Type V), prenylbisabolane-type (Type VI) and miscellaneous type (Type VII). On the basis of 170 references, this review covers the distribution, phytochemistry, synthesis and pharmacological activities of furanoditerpenoids, describing 444 compounds. The information provided in this review might shed light on further research and development of furanoditerpenoids as potential therapeutic agents.
资助项目	Science and Technology Development Fund[00000000] ; Macao S.A.R (FDCT)[120/2013/A3] ; Research Fund of University of Macau[MYRG2014-00020-ICMS-QRCM] ; Research Fund of University of Macau[MYRG2015-00153-ICMS-QRCM]
WOS关键词	CLERODANE-TYPE DITERPENOIDS ; REARRANGED NEOCLERODANE DITERPENOIDS ; LIVERWORT SCAPANIA-PARVA ; CAESALPINIA-SAPPAN LINN ; CASSANE-TYPE DITERPENES ; L. VAR SATIVA ; ABIETANE DITERPENOIDS ; LABDANE DITERPENES ; CIS-CLERODANE ; SALVINORIN-A
WOS研究方向	Plant Sciences
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000399019300003
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272722]
专题	天然药物化学研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Lin, Ligen
作者单位	1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Ave Univ, Taipa, Macau, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Bao, Han,Zhang, Qingwen,Ye, Yang,et al. Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities[J]. PHYTOCHEMISTRY REVIEWS,2017,16(2):235-270.
APA	Bao, Han,Zhang, Qingwen,Ye, Yang,&Lin, Ligen.(2017).Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities.PHYTOCHEMISTRY REVIEWS,16(2),235-270.
MLA	Bao, Han,et al."Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities".PHYTOCHEMISTRY REVIEWS 16.2(2017):235-270.