Assignment of the Absolute Configuration of Phosphoeleganin via Synthesis of Model Compounds

doi:10.1021/acs.jnatprod.7b00397

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	Assignment of the Absolute Configuration of Phosphoeleganin via Synthesis of Model Compounds
	Luciano, Paolo 1; Imperatore, Concetta 1; Senese, Maria 1; Aiello, Anna 1; Casertano, Marcello 1; Guo, Yue-W.2; Menne, Marialuisa 1
刊名	JOURNAL OF NATURAL PRODUCTS
	2017-07
卷号	80 期号:7 页码:2118-2123
ISSN号	0163-3864
DOI	10.1021/acs.jnatprod.7b00397
文献子类	Article
英文摘要	The full absolute configuration assignment of phosphoeleganin (1), a recently discovered marine-derived phosphorylated polyketide with protein tyrosine phosphatase 1B inhibitory activity, was achieved. It was based on the synthesis of model diasteroisomeric compounds of the C-8 C-12 segment portion of phosphoeleganin, chiral derivatization methods, and application of the universal NMR database concept.
资助项目	Regione Campania under POR Campania FESR-O.O. 2.1 (FarmaBioNet)[00000000] ; EU project Bluegenics[311848] ; Universita di Napoli Federico II under the STAR project (SeaLEADS)[00000000]
WOS关键词	NATURAL-PRODUCTS ; NMR
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000406818300020
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272579]
专题	新药研究国家重点实验室中科院受体结构与功能重点实验室
通讯作者	Menne, Marialuisa
作者单位	1.Univ Napoli Federico II, Dipartimento Farm, Via D Montesano,49, I-80131 Naples, Italy; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Chong Zhi Rd 555, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Luciano, Paolo,Imperatore, Concetta,Senese, Maria,et al. Assignment of the Absolute Configuration of Phosphoeleganin via Synthesis of Model Compounds[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(7):2118-2123.
APA	Luciano, Paolo.,Imperatore, Concetta.,Senese, Maria.,Aiello, Anna.,Casertano, Marcello.,...&Menne, Marialuisa.(2017).Assignment of the Absolute Configuration of Phosphoeleganin via Synthesis of Model Compounds.JOURNAL OF NATURAL PRODUCTS,80(7),2118-2123.
MLA	Luciano, Paolo,et al."Assignment of the Absolute Configuration of Phosphoeleganin via Synthesis of Model Compounds".JOURNAL OF NATURAL PRODUCTS 80.7(2017):2118-2123.