Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens

doi:10.1039/c8ra04226h

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 药理学第一研究室

	Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens
	Zhang, Shuaibing 2; Huang, Ying 1; He, Shijun3 ; Chen, Heping 2; Li, Zhenghui 2; Wu, Bin 2; Zuo, Jianping3 ; Feng, Tao 2; Liu, Jikai 2
刊名	RSC ADVANCES
	2018
卷号	8 期号:42 页码:23914-23918
ISSN号	2046-2069
DOI	10.1039/c8ra04226h
文献子类	Article
英文摘要	A chemical study of the common species Albatrellus confluens present in Yunnan province, southwest China led to the identification of a pair of epimers named albatredines A (1) and B (2). They feature a natural unprecedented 1,2,4-oxadiazolidin-5-one skeleton. The acyl substitution pattern and complete configurational assignments were deduced from the comparison between experimental and theoretical C-13 NMR and ECD data, respectively. Bioassay results showed that compound 1 exhibited a weak immunosuppressive activity against the concanavalin A-induced T lymphocyte cell proliferation (IC50 2.99 M).
资助项目	National Natural Science Foundation of China[81561148013] ; National Natural Science Foundation of China[81373289] ; Key Projects of Technological Innovation of Hubei Province[2016ACA138]
WOS关键词	DERIVATIVES ; ALBACONOL ; CULTURES ; ACID
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000437475600046
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/272308]
专题	药理学第一研究室中科院受体结构与功能重点实验室新药研究国家重点实验室
通讯作者	Zuo, Jianping; Feng, Tao; Liu, Jikai
作者单位	1.Leibniz Inst Nat Prod Res & Infect Biol HKI, Leibniz Res Grp Biobricks Microbial Nat Prod Synt, Adolf Reichwein Str 23, D-07745 Jena, Germany; 2.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Shuaibing,Huang, Ying,He, Shijun,et al. Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens[J]. RSC ADVANCES,2018,8(42):23914-23918.
APA	Zhang, Shuaibing.,Huang, Ying.,He, Shijun.,Chen, Heping.,Li, Zhenghui.,...&Liu, Jikai.(2018).Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens.RSC ADVANCES,8(42),23914-23918.
MLA	Zhang, Shuaibing,et al."Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens".RSC ADVANCES 8.42(2018):23914-23918.