Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines

doi:10.1016/j.tetlet.2011.01.058

	Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines
	Gan, Haifeng 2; Lu, Yunyu 2; Huang, Yue 2; Ni, Lijun 2; Xu, Jinyi 2; Yao, Hequan 2,3; Wu, Xiaoming 1,2
刊名	TETRAHEDRON LETTERS
	2011-03-23
卷号	52 期号:12 页码:1320-1324
ISSN号	0040-4039
DOI	10.1016/j.tetlet.2011.01.058
文献子类	Article
英文摘要	An environmental-benign methodology to synthesize 1-benzoylisoquinolines from 1-benzyl-3, 4-dihydroisoquinolines or 1-benzyl-1,2,3,4- tetrahydroisoquinolines using dioxygen as an oxidant was developed. This methodology in combination with Bischler-Napieralski reaction leads to a facile synthesis of 1-benzoylisoquinolines from phenylacetic acids and phenylethanamines. (C) 2011 Elsevier Ltd. All rights reserved.
资助项目	National Natural Science Foundation[20902111] ; Ministry of Education of China[NCET-2008] ; State Key Laboratory of Drug Research[SIMM0901KF-04] ; Fundamental Research Funds for the Central Universities[JKZ2009002] ; Fundamental Research Funds for the Central Universities[JKY2009013]
WOS关键词	BIOLOGICAL EVALUATION ; MEDIATED OXIDATION ; CELL-CYCLE ; ALKALOIDS ; ISOQUINOLINES ; LIRIODENINE ; INHIBITORS ; BENZYLISOQUINOLINE ; DERIVATIVES ; APORPHINES
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000288044700021
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/278577]
专题	中国科学院上海药物研究所
通讯作者	Yao, Hequan
作者单位	1.China Pharmaceut Univ, Ctr Drug Discovery, Nanjing 210009, Jiangsu, Peoples R China; 2.China Pharmaceut Univ, Sch Pharm, Dept Med Chem, Nanjing 210009, Jiangsu, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Gan, Haifeng,Lu, Yunyu,Huang, Yue,et al. Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines[J]. TETRAHEDRON LETTERS,2011,52(12):1320-1324.
APA	Gan, Haifeng.,Lu, Yunyu.,Huang, Yue.,Ni, Lijun.,Xu, Jinyi.,...&Wu, Xiaoming.(2011).Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines.TETRAHEDRON LETTERS,52(12),1320-1324.
MLA	Gan, Haifeng,et al."Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines".TETRAHEDRON LETTERS 52.12(2011):1320-1324.