Diterpenoids from the fruits of Rhododendron molle

	Diterpenoids from the fruits of Rhododendron molle
	Li, CJ ; Liu, H; Wang, LQ ; Jin, MW ; Chen, SN ; Bao, GH ; Qin, GW
刊名	ACTA CHIMICA SINICA
	2003-07
卷号	61 期号:7 页码:1153-1156
关键词	Rhododendron molle rhodomolleins XIX and XX rhodojaponin III sodium channel antagonist
ISSN号	0567-7351
文献子类	Article
英文摘要	Studies on the fruits of Rhododendron molle led to isolation of two new diterpenoids rhodomolleins XIX (1) and XX (2) together with a known diterpenoid rhodojaponin III (3). Their structures were elucidated on the basis of spectroscopic data. The effect of 3 on sodium channel of isolated guinea-pig ventricular myocytes, was also studied. In the whole cell patch-clamp mode, 3 decreased sodium current remarkably (p < 0.05), which suggested that 3 was an effective sodium channel antagonist.
WOS关键词	SODIUM CURRENT ; VENTRICULAR CELLS ; QUINIDINE ; LIDOCAINE
WOS研究方向	Chemistry
语种	中文
CSCD记录号	CSCD:1174438
出版者	SCIENCE PRESS
WOS记录号	WOS:000184988400034
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/274212]
专题	中国科学院上海药物研究所
通讯作者	Qin, GW
作者单位	1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Physiol, Wuhan 430030, Peoples R China
推荐引用方式 GB/T 7714	Li, CJ,Liu, H,Wang, LQ,et al. Diterpenoids from the fruits of Rhododendron molle[J]. ACTA CHIMICA SINICA,2003,61(7):1153-1156.
APA	Li, CJ.,Liu, H.,Wang, LQ.,Jin, MW.,Chen, SN.,...&Qin, GW.(2003).Diterpenoids from the fruits of Rhododendron molle.ACTA CHIMICA SINICA,61(7),1153-1156.
MLA	Li, CJ,et al."Diterpenoids from the fruits of Rhododendron molle".ACTA CHIMICA SINICA 61.7(2003):1153-1156.