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Synthesis and cytotoxicity evaluation of some isoquinoline derivatives related to 1-arylnaphthalene lignans
Ding, HX; Lu, W; Zhou, CX; Li, HB; Yang, LX; Zhang, QJ; Wu, XM; Baudoin, O; Cai, JC; Gueritte, F
刊名CHINESE CHEMICAL LETTERS
2005-10
卷号16期号:10页码:1279-1282
关键词isoquinoline derivatives 1-arylnaphthalene lignans synthesis cytotoxicity
ISSN号1001-8417
文献子类Article
英文摘要Two series of novel compounds designed as hybrids of 1-arylnaphthalene lignans with dihydroisoquinolines or isoquinolines were synthesized and evaluated for their cytotoxicities on human tumor cell lines, such as A549, Hela, PC-3 and KB. Some of the synthetic compounds exhibited their IC50 values on selected cell lines at gmol/L scale.
WOS关键词ANTITUMOR-ACTIVITY ; PODOPHYLLOTOXIN ; ANALOGS
WOS研究方向Chemistry
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000232638500001
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/273796]  
专题中国科学院上海药物研究所
通讯作者Zhao, Y
作者单位1.Zhejiang Hisun Naturelite Pharmaceut R&D Co, Hangzhou 310006, Peoples R China
2.Zhejiang Univ, Dept Tradit Chinese Med & Nat Drug Res, Coll Pharmaceut Sci, Hangzhou 31003, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
4.CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France
推荐引用方式
GB/T 7714
Ding, HX,Lu, W,Zhou, CX,et al. Synthesis and cytotoxicity evaluation of some isoquinoline derivatives related to 1-arylnaphthalene lignans[J]. CHINESE CHEMICAL LETTERS,2005,16(10):1279-1282.
APA Ding, HX.,Lu, W.,Zhou, CX.,Li, HB.,Yang, LX.,...&Zhao, Y.(2005).Synthesis and cytotoxicity evaluation of some isoquinoline derivatives related to 1-arylnaphthalene lignans.CHINESE CHEMICAL LETTERS,16(10),1279-1282.
MLA Ding, HX,et al."Synthesis and cytotoxicity evaluation of some isoquinoline derivatives related to 1-arylnaphthalene lignans".CHINESE CHEMICAL LETTERS 16.10(2005):1279-1282.
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