Review of relationship between vascular endothelial growth factor family & receptors and tumor angiogenesis

	Review of relationship between vascular endothelial growth factor family & receptors and tumor angiogenesis
	Chen Shan 2; Jin Wei 2; Min Ping 2; Lu He 1
刊名	Chinese Bulletin of Life Sciences
	2004
卷号	16 期号:1 页码:19-23
关键词	vascular endothelial growth factor vascular endothelial growth factors receptors angiogenesis
ISSN号	1004-0374
其他题名	血管内皮生长因子家族及其受体与肿瘤血管生成研究进展
文献子类	Review
英文摘要	Vascular endothelial growth factor (VEGF) also named vascular permeability factor (VPF), is an impor-tant positive regulator for angiogenesis. This is one target of the anticancer research. Discovered members of VEGF family include: VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E and placenta growth factor (PLGF). Recep-tors of VEGF are VEGFR-l(flt-l), VEGFR-2(flk-l/KDR), VEGFR-3(flt-4) and neuropilin(NPRl/NPR2). Mem-bers of this family can selectively promote mitosis of vascular endotheial cells or lymphatic endothelial cells, stimu-late endothelial cells to proliferate and induce angiogenesis. They also enhance the permeability of microvessels, help to establish capillary vessels net. This article mainly reviewed the structures, functional characteristics, rela-tionship between VEGF and its inhibitors and tumor angiogenesis.
WOS研究方向	General & Internal Medicine (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:1507915
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/268401]
专题	中国科学院上海药物研究所
作者单位	1.Le pole franco-chinois du science du vivant et genomique, Ruijin Hospital, Shanghai 200025, China. 2.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.;
推荐引用方式 GB/T 7714	Chen Shan,Jin Wei,Min Ping,et al. Review of relationship between vascular endothelial growth factor family & receptors and tumor angiogenesis[J]. Chinese Bulletin of Life Sciences,2004,16(1):19-23.
APA	Chen Shan,Jin Wei,Min Ping,&Lu He.(2004).Review of relationship between vascular endothelial growth factor family & receptors and tumor angiogenesis.Chinese Bulletin of Life Sciences,16(1),19-23.
MLA	Chen Shan,et al."Review of relationship between vascular endothelial growth factor family & receptors and tumor angiogenesis".Chinese Bulletin of Life Sciences 16.1(2004):19-23.