Studies on uranium mobilization agents VI: synthesis of 2,3-dihydroxy-4-carbomethoxybenzyl aminocarboxylic acid amides chelating agents

	Studies on uranium mobilization agents VI: synthesis of 2,3-dihydroxy-4-carbomethoxybenzyl aminocarboxylic acid amides chelating agents
	Qin, Z H; Xie, Y Y
	1993
卷号	28
期号	8
页码	619-22
英文摘要	In searching for new chelation therapy drugs against uranium intoxication, a series of N-carboxymethyl-N-(substituted carbamoylmethyl)-2,3-dihydroxy-4-carbomethoxybenzylamine was synthesized starting with o-vanillin. The effect on detoxication of UO2(NO3)2, CuSO4 and NiCl2 in mice was tested. Some of them (IVa, IVd, IVf and IVg) were shown to be good antidotes for acute uranium intoxication, but all were less effective for Cu2+ and Ni2+.
会议录	Yao xue xue bao = Acta pharmaceutica Sinica
文献子类	Meeting Abstract;Article
语种	中文
内容类型	会议论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266869]
专题	中国科学院上海药物研究所
作者单位	Shanghai Institute of Materia Medica, Academia Sinica
推荐引用方式 GB/T 7714	Qin, Z H,Xie, Y Y. Studies on uranium mobilization agents VI: synthesis of 2,3-dihydroxy-4-carbomethoxybenzyl aminocarboxylic acid amides chelating agents[C]. 见:.