Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus

doi:10.1093/femsle/fny056

	Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus
	Cai, Jia-Yi 3; Wang, Yuan-Yuan 3; Ma, Kai 3; Hou, Yong-Na 3; Yao, Guo-Dong 4; Hayashi, Toshihiko 3; Itoh, Kikuji 5; Tashiro, Shin-Ichi 1; Onodera, Satoshi 2; Ikejima, Takashi 3
刊名	FEMS microbiology letters
	2018-04-01
卷号	365 期号:8
ISSN号	1574-6968
DOI	10.1093/femsle/fny056
文献子类	Article
英文摘要	This study demonstrates that growth of Staphylococcus aureus in the presence of salicylate reduces ultraviolet C (UVC)-induced cell death and increases the generation of reactive oxygen species (ROS). In addition, compounds that scavenge ROS (N-acetylcysteine, glutathione, catalase and superoxide dismutase) reverse the increased UVC survival induced by growth in the presence of salicylate, while ROS donors (tert-butylhydroperoxide, H2O2 and NaClO) enhance survival of salicylate challenged cultures. Collectively, these findings suggest that ROS production induced by growth in the presence of salicylate protects S. aureus from UVC-induced cell death.
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266608]
专题	中国科学院上海药物研究所
作者单位	1.Department of Medical Education & Primary Care, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan; 2.Department of Clinical and Pharmaceutical Sciences, Showa Pharmaceutical University, Tokyo 194-8543, Japan 3.China-Japan Research Institute of Medical and Pharmaceutical Sciences, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China; 4.School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, China; 5.Biochemical Center, Japan SLC, Inc., Shizuoka 431-1103, Japan;
推荐引用方式 GB/T 7714	Cai, Jia-Yi,Wang, Yuan-Yuan,Ma, Kai,et al. Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus[J]. FEMS microbiology letters,2018,365(8).
APA	Cai, Jia-Yi.,Wang, Yuan-Yuan.,Ma, Kai.,Hou, Yong-Na.,Yao, Guo-Dong.,...&Ikejima, Takashi.(2018).Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus.FEMS microbiology letters,365(8).
MLA	Cai, Jia-Yi,et al."Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus".FEMS microbiology letters 365.8(2018).