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Different fingerprinting strategies to differentiate Porana sinensis and plants of Erycibe by high-performance liquid chromatography with diode array detection, ultra high performance liquid chromatography with tandem quadrupole mass spectrometry, and chemometrics
Chen, Zhiyong1,2; Liao, Liping; Yang, Yuanyuan; Zhang, Zijia; Wang, Zhengtao
刊名Journal of separation science
2015-01
卷号38期号:2页码:231-8
ISSN号1615-9314
DOI10.1002/jssc.201400861
文献子类Article
英文摘要Plants of Erycibe are widely used in traditional Chinese medicine for the treatment of joint pain and rheumatoid arthritis. With the reduction of Erycibe resources in the wild, Porana sinensis has been widely used as a substitute. However, it is important to understand the chemical distinctions between the two kinds of plants and identify their individual chemical markers. In this study, multiwavelength chromatographic fingerprint and precursor ion fingerprint techniques were used in conjunction with chemometric tools to fingerprint and thus differentiate between plant samples. The similar results obtained from different fingerprints prove the reliability of the two fingerprints. Results obtained from principal component analysis and orthogonal projection to latent structures discriminant analysis identified similarities between the chemical components of P. sinensis and plants of Erycibe. However, concentrations of 4-caffeoylquinic acid, 3,5-dicaffeoylquinic acid, 3,4-dicaffeoylquinic acid, and 4,5-dicaffeoylquinic acid were higher in P. sinensis than in plants of Erycibe, suggesting that P. sinensis may be more effective in medical treatments of some diseases than Erycibe.
语种英语
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/266416]  
专题中国科学院上海药物研究所
作者单位1.Department of Pharmacognosy, China Pharmaceutical University, Nanjing, P. R. China
2.The MOE Key Laboratory for Standardization of Chinese Medicines and The Shanghai Key Laboratory for Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, P. R. China;
推荐引用方式
GB/T 7714
Chen, Zhiyong,Liao, Liping,Yang, Yuanyuan,et al. Different fingerprinting strategies to differentiate Porana sinensis and plants of Erycibe by high-performance liquid chromatography with diode array detection, ultra high performance liquid chromatography with tandem quadrupole mass spectrometry, and chemometrics[J]. Journal of separation science,2015,38(2):231-8.
APA Chen, Zhiyong,Liao, Liping,Yang, Yuanyuan,Zhang, Zijia,&Wang, Zhengtao.(2015).Different fingerprinting strategies to differentiate Porana sinensis and plants of Erycibe by high-performance liquid chromatography with diode array detection, ultra high performance liquid chromatography with tandem quadrupole mass spectrometry, and chemometrics.Journal of separation science,38(2),231-8.
MLA Chen, Zhiyong,et al."Different fingerprinting strategies to differentiate Porana sinensis and plants of Erycibe by high-performance liquid chromatography with diode array detection, ultra high performance liquid chromatography with tandem quadrupole mass spectrometry, and chemometrics".Journal of separation science 38.2(2015):231-8.
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