Systematical analysis of multiple components in drainage bear bile powder from different sources

doi:10.19540/j.cnki.cjcmm.20180125.001

	Systematical analysis of multiple components in drainage bear bile powder from different sources
	Wang, Jie 2; Xiong, Ai-Zhen 2; Cheng, Rong-Rong 2; Yang, Li 2; Wang, Zheng-Tao 2; Liu, Shao-Yong 1
刊名	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
	2018-06
卷号	43 期号:11 页码:2326-2332
ISSN号	1001-5302
DOI	10.19540/j.cnki.cjcmm.20180125.001
文献子类	Meeting Abstract;Article
英文摘要	Bear Bile Powder contains bile acids, protein, amino acids, bilirubin and microelements and other compounds. Among them, the bile acids are the most active components. Currently, there are many studies on bile acids, but few reports on other components. Therefore, the purpose of this study is to carry out a systematical analysis of multiple components in drainage Bear Bile Powder from different sources. Bilirubin and protein were quantified by microplate spectrophotometer. The contents of bile acids and amino acids were determined by liquid chromatography coupled with mass spectrometry (LC-MS). The contents of microelements were determined by inductively coupled plasma mass spectrometry (ICP-MS) The result indicated that among 20 batches of bear bile powder from different sources there is high similarity (0.922-0.977). Tauroursodeoxycholic acid (TUDCA) and taurochenodeoxycholic acid (TCDCA) were the two most abundant components. The total contents of them were 41%-59% and met the current standard for quality control of bear bile powder. However, significant differences were found in their contents among samples from different sources. Besides, bilirubin, protein, amino acids and microelements also contributed to the differentiation of samples from different sources. The main components of bear bile powder from the different sources were with satisfactory similarity. But bile acids, bilirubin, protein, amino acids and microelements all contributed to the different among samples. Our present study provided a systematical approach for the better quality control and evaluation of bear bile powder.
语种	中文
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266372]
专题	中国科学院上海药物研究所
作者单位	1.Shanghai Kai Bao Pharmaceutical Co., Ltd., Shanghai 201401, China 2.The Key Laboratory of Standardization of Chinese Medicines of Ministry of Education, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;
推荐引用方式 GB/T 7714	Wang, Jie,Xiong, Ai-Zhen,Cheng, Rong-Rong,et al. Systematical analysis of multiple components in drainage bear bile powder from different sources[J]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,2018,43(11):2326-2332.
APA	Wang, Jie,Xiong, Ai-Zhen,Cheng, Rong-Rong,Yang, Li,Wang, Zheng-Tao,&Liu, Shao-Yong.(2018).Systematical analysis of multiple components in drainage bear bile powder from different sources.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,43(11),2326-2332.
MLA	Wang, Jie,et al."Systematical analysis of multiple components in drainage bear bile powder from different sources".Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 43.11(2018):2326-2332.