Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues

	Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues
	Zhou, Mao-Jin; Chen, Xiao-Yan; Zhong, Da-Fang
刊名	Yao xue xue bao = Acta pharmaceutica Sinica
	2007-05
卷号	42 期号:5 页码:520-4
ISSN号	0513-4870
文献子类	Article
英文摘要	To study the metabolism of trans-resveratrol-3-O-glucoside (TRG) in vitro in rat tissues, the incubation with cell-free extracts from rat stomach, duodenum, jejunum, ileum and liver was performed, separately. After TRG was incubated with the tissue extracts at 37 degrees C for up to 90 min, the deglycosylation of TRG was (3.50 +/- 0.24) % for stomach, (65.7 +/- 5.94)% for duodenum, (83.5 +/- 6.43)% for jejunum, (77.6 +/- 6.26)% for ileum and (9.62 +/- 1.21)% for liver, separately. It was observed that the small intestine extracts were more active in deglycosylation of TRG than the liver extract, which suggested that the small intestine mucosa played an important role in deglycosylation of TRG. It was assumed that the deglycosylation of TRG was catalyzed by beta-glucosidase in small intestine mucosa.
语种	中文
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266275]
专题	中国科学院上海药物研究所
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China
推荐引用方式 GB/T 7714	Zhou, Mao-Jin,Chen, Xiao-Yan,Zhong, Da-Fang. Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues[J]. Yao xue xue bao = Acta pharmaceutica Sinica,2007,42(5):520-4.
APA	Zhou, Mao-Jin,Chen, Xiao-Yan,&Zhong, Da-Fang.(2007).Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues.Yao xue xue bao = Acta pharmaceutica Sinica,42(5),520-4.
MLA	Zhou, Mao-Jin,et al."Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues".Yao xue xue bao = Acta pharmaceutica Sinica 42.5(2007):520-4.