The Cox-Aalen model for recurrent-event data with a dependent terminal event

doi:10.1111/stan.12167

CORC > 数学与系统科学研究院 > 中国科学院数学与系统科学研究院 > 应用数学研究所

	The Cox-Aalen model for recurrent-event data with a dependent terminal event
	Qu, Lianqiang 2; Sun, Liuquan1
刊名	STATISTICA NEERLANDICA
	2019-05-01
卷号	73 期号:2 页码:234-255
关键词	Cox-Aalen model estimating equation recurrent events share frailty terminal event
ISSN号	0039-0402
DOI	10.1111/stan.12167
英文摘要	Recurrent events with a dependent terminal event arise frequently in a wide variety of fields. In this paper, we propose a new joint model to analyze these data and model the dependence between recurrent and terminal events through shared gamma frailty. Specifically, a Cox-Aalen rate frailty model is specified for the recurrent event, and an additive hazards frailty model is specified for the terminal event. An estimating equation approach is developed for the parameters in the joint model, and the asymptotic properties of the proposed estimators are established. Simulation studies demonstrate that the proposed estimators perform well with finite samples. An application to a medical cost study of chronic heart failure patients is illustrated.
资助项目	National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of Random Complex Structures and Data Science, Chinese Academy of Sciences[2008DP173182] ; Fundamental Research Funds for the Central Universities[20205180090]
WOS研究方向	Mathematics
语种	英语
出版者	WILEY
WOS记录号	WOS:000466377800006
内容类型	期刊论文
源URL	[http://ir.amss.ac.cn/handle/2S8OKBNM/34604]
专题	应用数学研究所
通讯作者	Sun, Liuquan
作者单位	1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China 2.Cent China Normal Univ, Sch Math & Stat, Wuhan 430079, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Qu, Lianqiang,Sun, Liuquan. The Cox-Aalen model for recurrent-event data with a dependent terminal event[J]. STATISTICA NEERLANDICA,2019,73(2):234-255.
APA	Qu, Lianqiang,&Sun, Liuquan.(2019).The Cox-Aalen model for recurrent-event data with a dependent terminal event.STATISTICA NEERLANDICA,73(2),234-255.
MLA	Qu, Lianqiang,et al."The Cox-Aalen model for recurrent-event data with a dependent terminal event".STATISTICA NEERLANDICA 73.2(2019):234-255.