Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons

doi:10.1016/j.dsr.2019.103082

CORC > 海洋研究所 > 中国科学院海洋研究所 > 深海极端环境与生命过程研究中心

	Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons
	Wang, Hao 2,4; Zhang, Huan 2,4; Wang, Minxiao 2,3; Chen, Hao2,4 ; Lian, Chao 2,4; Li, Chaolun1,2,3,4
刊名	DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS
	2019-09-01
卷号	151 页码:11
关键词	Symbiosis RNA-Seq Comparative transcriptomic Bathymodiolin Deep-sea Adaptation
ISSN号	0967-0637
DOI	10.1016/j.dsr.2019.103082
通讯作者	Li, Chaolun(Icl@qdio.ac.cri)
英文摘要	Bathymodiolus platifrons adapted the chemosynthetic ecosystems, both cold seeps and hydrothermal vents, by harbouring gill symbionts. To survive these extreme and volatile ecological niches, the host mussel must be able to strictly regulate the symbionts in response to the environmental fluctuations. However, despite the research efforts, the molecular mechanisms governing host-symbiont interaction in deep-sea mussels are still largely unknown. Here, using the model deep-sea mussel Bathymodiolus plantiforns, we profiled the transcriptomic dynamic of the mussel gill during the loss and re-contact with symbionts with RNA-seq technology. The analysis of DEGs between untreated and symbiont loss samples revealed that metabolic and cellular organizational changes in the gill were associated with increased ribosomal activities, ubiquitin-proteasome systems, and autophagy. Meanwhile, the DE immune genes suggest that the host recognizes and interacts with endosymbionts through the pattern recognizing receptors, especially the Toll-like receptors. In addition, the DEGs between symbionts treated and environmental bacteria treated samples shed light on the mechanism of symbiont recognition. The symbionts treatment not only partially reversed the transcriptomic changes caused by symbiont-loss, but also suppressed host immune system which might facilitate the symbionts' entrance and survival in the host bacteriocytes. All together, these results suggest that the host-symbiont system in B. platifrons is tightly regulated but also with plasticity to fit environmental fluctuations.
资助项目	National Key R&D Program of China[2018YFC0310800] ; Scientific and Technological Innovation Project from Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14] ; Senior User Project of RV KEXUE[KEXUE2016G06]
WOS研究方向	Oceanography
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000488141500007
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/163238]
专题	海洋研究所_深海极端环境与生命过程研究中心
通讯作者	Li, Chaolun
作者单位	1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao, Shandong, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Shandong, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Ctr Deep Sea Res, Qingdao, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Hao,Zhang, Huan,Wang, Minxiao,et al. Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons[J]. DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS,2019,151:11.
APA	Wang, Hao,Zhang, Huan,Wang, Minxiao,Chen, Hao,Lian, Chao,&Li, Chaolun.(2019).Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons.DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS,151,11.
MLA	Wang, Hao,et al."Comparative transcriptomic analysis illuminates the host-symbiont interactions in the deep-sea mussel Bathymodiolus platifrons".DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS 151(2019):11.