synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes

	synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes
	Yu KC(俞开潮)1; Wan FX(万福贤)1; Zhang Y(张焱)1; Zhou JL(周锦兰)1; Lu G(卢广)2; Liu ML(刘买利)2; Ding SW(丁尚武)2
刊名	chinesejournalofinorganicchemistry
	2004
卷号	20 期号:4 页码:389
ISSN号	1001-4861
英文摘要	Four new ester-amido ligands were synthesized by esterification of mono-iso-butyl diethylenetriaminepentaacetate and mono-iso-butyl ethylenediaminetetraacetate with N,N'-ethylene bis-lactamide and NN'-1,6-hexamethylenebislactamide, respectively. The corresponding Gd(III) complexes were made by reacting the ligands with Gd2O3. All ligands and complexes were characterized: by FT-IR, H-1 NMR and elemental analysis. The measured longitudinal relaxivity of these complexes were all higher than that of Gd-DTPA. The investigation on cute toxicity and T-1-weighted imaging of complex derived from mono-N,N'-ethylenebislactamide ester diethlenetriaminepentaacetate were performed. No cute toxicity was found. The tested complex exhibited the higher enhancement on MRI signal intensity in rat liver, comparing with Gd-DTPA.
语种	英语
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/17075]
专题	中国科学院武汉物理与数学研究所
作者单位	1.华中科技大学 2.中国科学院武汉物理与数学研究所
推荐引用方式 GB/T 7714	Yu KC,Wan FX,Zhang Y,et al. synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes[J]. chinesejournalofinorganicchemistry,2004,20(4):389.
APA	俞开潮.,万福贤.,张焱.,周锦兰.,卢广.,...&丁尚武.(2004).synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes.chinesejournalofinorganicchemistry,20(4),389.
MLA	俞开潮,et al."synthesisandmrirelaxationenhancementofmonoexteramidogadoliniumcomplexes".chinesejournalofinorganicchemistry 20.4(2004):389.