Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish

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	Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish
	Jiang, WS; Guo, YC; Yang, KF; Shi, Q; Yang, JX
刊名	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
	2019
卷号	20 期号:4
ISSN号	1422-0067
英文摘要	Body size is one of the most important attributes of a species, but the basic question of why and how each species reaches a different right size is still largely unknown. Herein, three phylogenetically closely related catfishes from Sisoridae, including one extraordinarily large-sized Bagarius yarrelli and two average-sized Glyptothorax macromaculatus and Oreoglanis setiger, were comparatively studied using RNA-Seq. Approximately 17,000 protein-coding genes were annotated for each of the three fishes, and 9509 genes were identified as high-confidence orthologous gene pairs. Comparative expressions uncovered a similar functional cluster about ribosome biogenesis was enriched in different tissues of the upregulated genes of Bagarius yarrelli. Moreover, differentially expressed genes and positively selected genes revealed that the glycolysis/pyruvate metabolism and cell cycle pathways have also greatly enhanced in this large-sized species. In total, 20 size-related candidate genes (including two growth modulators: the serine/threonine-protein kinases 3 (AKT3) and adaptor protein 1 (SH2B1), and a crucial pyruvate kinase (PKM2A)) were identified by multiplying comparative analyses along with gene functional screening, which would play major roles in enabling the large body size associated with Bagarius yarrelli and provide new insights into body size evolution. In conjunction with field observations and morphological comparisons, we hypothesize that habitat preferences promote size divergence of sisorids.
语种	英语
内容类型	期刊论文
源URL	[http://ir.kiz.ac.cn:8080/handle/152453/12561]
专题	昆明动物研究所_系统进化与生物地理学
推荐引用方式 GB/T 7714	Jiang, WS,Guo, YC,Yang, KF,et al. Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2019,20(4).
APA	Jiang, WS,Guo, YC,Yang, KF,Shi, Q,&Yang, JX.(2019).Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,20(4).
MLA	Jiang, WS,et al."Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20.4(2019).