Diastereoselective and Enantioselective Desymmetrization of alpha-Substituted Cyclohexadienones via Intramolecular Stetter Reaction

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	Diastereoselective and Enantioselective Desymmetrization of alpha-Substituted Cyclohexadienones via Intramolecular Stetter Reaction
	Jia MQ(贾敏强) ; Liu C(刘川) ; You SL(游书力)
刊名	J. Org. Chem.
	2012
卷号	77 期号:23 页码:10996-11001
ISSN号	0022-3263
其他题名	通过分子内Stetter反应对α-取代的环己二酮的非对映选择性和不对称去对称化
通讯作者	游书力
英文摘要	Highly diastereoselective and enantioselective desymmetrization of alpha-substituted cyclohexadienones via NHC-catalyzed intramolecular Stetter reaction was realized. Amino-indanol derived triazolium salt bearing a C6F5 group was found to be the optimal catalyst precursor in the intramolecular Stetter reaction furnishing tricyclic products bearing multi-stereocenters in up to 96% yield and >99% ee.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/jo3022555
语种	英语
WOS记录号	WOS:000311926100060
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28195]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Jia MQ,Liu C,You SL. Diastereoselective and Enantioselective Desymmetrization of alpha-Substituted Cyclohexadienones via Intramolecular Stetter Reaction[J]. J. Org. Chem.,2012,77(23):10996-11001.
APA	贾敏强,刘川,&游书力.(2012).Diastereoselective and Enantioselective Desymmetrization of alpha-Substituted Cyclohexadienones via Intramolecular Stetter Reaction.J. Org. Chem.,77(23),10996-11001.
MLA	贾敏强,et al."Diastereoselective and Enantioselective Desymmetrization of alpha-Substituted Cyclohexadienones via Intramolecular Stetter Reaction".J. Org. Chem. 77.23(2012):10996-11001.