Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines

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	Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines
	Zhou YY(周友运) ; Wang LJ(王丽佳) ; Li J(李军) ; Sun XL(孙秀丽) ; Tang Y(唐勇)
刊名	J. Am. Chem. Soc.
	2012
卷号	134 期号:22 页码:9066-9069
ISSN号	0002-7863
其他题名	边臂促进的胺对D-A环丙烷的高对映选择性开环反应及其动力学拆分的研究
通讯作者	孙秀丽 ; 唐勇
英文摘要	A Ni-catalyzed asymmetric ring-opening reaction of 2-substituted cyclopropane-1,1-dicarboxylates with aliphatic amines has been accomplished using the chiral indane-trisoxazoline (In-TOX) ligand. This highly enantioselective reaction provides an efficient approach to a variety of chiral gamma-substituted gamma-amino acid derivatives, which are readily transformed into multifunctionalized piperidines and gamma-lactams. The single-crystal X-ray structure of the TOX-Ni complex is provided, and the role of the side arm in the chiral ligand is discussed.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ja302691r
语种	英语
WOS记录号	WOS:000304837800012
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/27973]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Zhou YY,Wang LJ,Li J,et al. Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines[J]. J. Am. Chem. Soc.,2012,134(22):9066-9069.
APA	周友运,王丽佳,李军,孙秀丽,&唐勇.(2012).Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines.J. Am. Chem. Soc.,134(22),9066-9069.
MLA	周友运,et al."Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines".J. Am. Chem. Soc. 134.22(2012):9066-9069.