Synthesis of Symmetrical and Unsymmetrical N,N '-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate

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	Synthesis of Symmetrical and Unsymmetrical N,N '-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate
	Xing H(邢辉) ; Zhang Y(张烨) ; Lai YS(赖宜生) ; Jiang YW(蒋咏文) ; Ma DW(马大为)
刊名	J. Org. Chem.
	2012
卷号	77 期号:12 页码:5449-5453
ISSN号	0022-3263
其他题名	铜/N-甲基甘氨酸催化的硝酸胍的芳基化合成对称和不对称的N,N'-二芳基胍
通讯作者	赖宜生 ; 马大为
英文摘要	CuI/N-methylglycine-catalyzed coupling reaction of guanidine nitrate with both aryl iodides and bromides takes place at 70-100 degrees C, affording symmetrical N,N'-diaryl guanidines with good to excellent yields. Unsymmetrical N,N'-diaryl guanidines can be assembled via monoarylation of guanidine nitrate with aryl iodides bearing a strong electron-withdrawing group and subsequent coupling with another aryl iodide.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/jo300840x
语种	英语
WOS记录号	WOS:000305205400030
公开日期	2013-08-22
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/27967]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Xing H,Zhang Y,Lai YS,et al. Synthesis of Symmetrical and Unsymmetrical N,N '-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate[J]. J. Org. Chem.,2012,77(12):5449-5453.
APA	邢辉,张烨,赖宜生,蒋咏文,&马大为.(2012).Synthesis of Symmetrical and Unsymmetrical N,N '-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate.J. Org. Chem.,77(12),5449-5453.
MLA	邢辉,et al."Synthesis of Symmetrical and Unsymmetrical N,N '-Diaryl Guanidines via Copper/N-Methylglycine-Catalyzed Arylation of Guanidine Nitrate".J. Org. Chem. 77.12(2012):5449-5453.