Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar

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	Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar
	Fan SL(樊士璐) ; He CY(贺春阳) ; Zhang XG(张新刚)
刊名	Tetrahedron
	2010
卷号	66 期号:27-28 页码:5218-5228
ISSN号	0040-4020
其他题名	立体选择性合成炔丙基氟化合物及其在单氟代糖合成中的应用
通讯作者	张新刚
英文摘要	An effective method to diastereoselectively synthesize enantioenriched propargylic fluorides was developed via S(N)1 type reaction of DAST participated dehydroxy-fluorination of diastereomeric propargylic alcohol cobalt carbonyl complexes. A serious of propargylic fluorides can be prepared by this approach in good yields with moderate to high diastereoselectivities. To demonstrate the application of this approach in synthesis, monofluorinated sugar 12, an important and versatile building block, was prepared in an efficient manner. (C) 2010 Elsevier Ltd. All rights reserved.
学科主题	氟化学 ; 金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tet.2010.04.078
语种	英语
WOS记录号	WOS:000279126700042
公开日期	2013-08-23
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28209]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Fan SL,He CY,Zhang XG. Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar[J]. Tetrahedron,2010,66(27-28):5218-5228.
APA	樊士璐,贺春阳,&张新刚.(2010).Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar.Tetrahedron,66(27-28),5218-5228.
MLA	樊士璐,et al."Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar".Tetrahedron 66.27-28(2010):5218-5228.