Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate

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	Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate
	Min QQ(闵巧桥) ; He CY(贺春阳) ; Zhou HB(周海滨) ; Zhang XG(张新刚)
刊名	Chem. Commun.
	2010
卷号	46 期号:42 页码:8029-8031
ISSN号	1359-7345
其他题名	基于手性三氟丙酮酸酯亚胺高立体选择性合成alpha-三氟甲基-alpha-氨基酸
通讯作者	张新刚
英文摘要	An efficient method for highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids was developed via indium mediated allylation of (R)-phenylglycinol methyl ether based imines of trifluoropyruvate in good yields with high diastereoselectivities at room temperature; to illustrate the application of this method in organic synthesis, 2-allyl-2-(trifluoromethyl) aziridine was prepared in an efficient manner.
学科主题	氟化学 ; 金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1039/c0cc02408b
语种	英语
WOS记录号	WOS:000283260400049
公开日期	2013-08-23
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/28203]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Min QQ,He CY,Zhou HB,et al. Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate[J]. Chem. Commun.,2010,46(42):8029-8031.
APA	闵巧桥,贺春阳,周海滨,&张新刚.(2010).Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate.Chem. Commun.,46(42),8029-8031.
MLA	闵巧桥,et al."Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate".Chem. Commun. 46.42(2010):8029-8031.