Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans

doi:10.1016/j.ecoenv.2018.09.008

	Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans
	Yang, Yaning 3,4; Xu, Guangmin 1,3; Xu, Shengmin 1,3; Chen, Shaopeng 1,3; Xu, An 1,3,4; Wu, Lijun 1,2,3,4
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2018-12-15
卷号	165 页码:291-298
关键词	Silver nanoparticles Ionic strength Bioaccumulation Toxicity Caenorhabditis elegans
ISSN号	0147-6513
DOI	10.1016/j.ecoenv.2018.09.008
通讯作者	Xu, Shengmin(shmxu@mail.ustc.edu.cn) ; Wu, Lijun(ljw@ipp.ac.cn)
英文摘要	The behavior of silver nanoparticles (AgNPs) is influenced by environmental factors which altered their bioaccumulation and toxicity. In this study, we comprehensively investigated the influence of ionic strength on the ecotoxicity of AgNPs to Caenorhabditis elegans (C. elegans) through the transfer from Escherichia coli (E. coli). Three different exposure media (deionized water, EPA water and KM) were used to pretreat AgNPs. E. coli was then exposed to these transformed AgNPs and fed to C. elegans. Our results indicated that ionic strength significantly enhanced the reproductive toxicity (germ cell corpses, brood size and lifespan) and neurotoxicity (head trash and body bend) of AgNPs in C. elegans. Moreover, ICP-MS analysis showed that higher ionic strength increased bioaccumulation of AgNPs in E. coli and the resulting Ag body burden of E. coli affected the transfer of AgNPs to C. elegans, which might be responsible for the increased toxicity to nematodes. Furthermore, we also found that the reactive oxygen species (ROS) level in C. elegans was significantly increased after exposed to E. coli contaminated with ionic strength-treated AgNPs, which might play another important role for the enhanced toxicity of AgNPs. Overall, this study showed that the bioavailability and potential ecotoxicity of AgNPs are associated with the environmental factors.
资助项目	National Basic Research 973 Program[2014CB932002] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB14030502] ; Key Program of 13th five-year plan, CASHIPS[KP-2017-05] ; National Natural Science Foundation of China[201707144] ; National Natural Science Foundation of China[21607157] ; Anhui Provincial Natural Science Foundation[1808085QB49]
WOS关键词	TITANIUM-DIOXIDE NANOPARTICLES ; TERRESTRIAL FOOD-CHAIN ; DAPHNIA-MAGNA ; ENGINEERED NANOPARTICLES ; RELEVANT CONCENTRATIONS ; MEDIA COMPOSITION ; TROPHIC TRANSFER ; BIOMAGNIFICATION ; BIOAVAILABILITY ; NANOSILVER
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000447484000035
资助机构	National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; National Basic Research 973 Program ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; Key Program of 13th five-year plan, CASHIPS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/39373]
专题	中国科学院合肥物质科学研究院
通讯作者	Xu, Shengmin; Wu, Lijun
作者单位	1.Key Lab Environm Toxicol & Pollut Control Technol, Hefei 230031, Anhui, Peoples R China 2.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, POB 1138, Hefei 230031, Anhui, Peoples R China 4.Univ Sci & Technol China, Sch Environm Sci & Optoelect Technol, Hefei 230026, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yaning,Xu, Guangmin,Xu, Shengmin,et al. Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2018,165:291-298.
APA	Yang, Yaning,Xu, Guangmin,Xu, Shengmin,Chen, Shaopeng,Xu, An,&Wu, Lijun.(2018).Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,165,291-298.
MLA	Yang, Yaning,et al."Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 165(2018):291-298.