Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters

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	Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters
	Wan XB(万小兵) ; Sun YH(孙延晖) ; Luo YF(罗云飞) ; Li D(李到) ; Zhang ZG(张兆国)
刊名	J. Org. Chem.
	2005
卷号	70 期号:3 页码:1070-1072
ISSN号	0022-3263
其他题名	Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters
通讯作者	张兆国
英文摘要	The synthesis and resolution of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed asymmetric hydrogenation reaction of beta-ketoesters are reported. Up to 99.5% ee was achieved. Under solvent-free reaction conditions, acetoacetates could be reduced with good enantioselectivity and high efficiency; a TON of 20 000 was obtained within 3.5 h. The results obtained were comparable to those when SEGPhos was applied.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/jo048466d
语种	英语
WOS记录号	WOS:000226777100045
公开日期	2013-08-14
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/27619]
专题	上海有机化学研究所_上海有机化学研究所
推荐引用方式 GB/T 7714	Wan XB,Sun YH,Luo YF,et al. Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters[J]. J. Org. Chem.,2005,70(3):1070-1072.
APA	万小兵,孙延晖,罗云飞,李到,&张兆国.(2005).Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters.J. Org. Chem.,70(3),1070-1072.
MLA	万小兵,et al."Synthesis of a bulky and electron-rich derivative of SEGPhos and its application in Ru-catalyzed enantioselective hydrogenation beta-ketoesters".J. Org. Chem. 70.3(2005):1070-1072.