Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro [imidazolidine-2-thione]bisoxindoles

	Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro [imidazolidine-2-thione]bisoxindoles
	Han, Yan-Yan ; Chen, Wen-Bing ; Han, Wen-Yong ; Wu, Zhi-Jun ; Zhang, Xiao-Mei ; Yuan, Wei-Cheng
刊名	ORGANIC LETTERS
	2012
卷号	14 期号:2 页码:490-493
ISSN号	1523-7060
通讯作者	Yuan, WC (reprint author), Chinese Acad Sci, Chengdu Inst Organ Chem, Natl Engn Res Ctr Chiral Drugs, Chengdu 610041, Peoples R China.
产权排序	2
英文摘要	An efficient and stereoselective reaction between 3-isothiocyanato oxindoles and isatins/isatinimines has been developed to afford structurally diverse dispiro[oxazolidine-2-thione]bisoxindoles and dispiro[imidazolidine-2-thione]bisoxindoles in excellent results under mild conditions. The potential of asymmetric induction by means of a chiral auxiliary was explored. The isomers are separable, and products could be isolated as single diastereomers by column chromatography. Further synthetic transformations of the reaction product were also successfully realized.
学科主题	Chemistry
收录类别	SCI
资助信息	National Natural Science Foundation of China [20802074]; National Basic Research Program of China (973 Program) [2010CB833300]; Sichuan Youth Science and Technology Foundation
语种	英语
WOS记录号	WOS:000299238600017
公开日期	2013-07-03
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23917]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Han, Yan-Yan,Chen, Wen-Bing,Han, Wen-Yong,et al. Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro [imidazolidine-2-thione]bisoxindoles[J]. ORGANIC LETTERS,2012,14(2):490-493.
APA	Han, Yan-Yan,Chen, Wen-Bing,Han, Wen-Yong,Wu, Zhi-Jun,Zhang, Xiao-Mei,&Yuan, Wei-Cheng.(2012).Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro [imidazolidine-2-thione]bisoxindoles.ORGANIC LETTERS,14(2),490-493.
MLA	Han, Yan-Yan,et al."Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro [imidazolidine-2-thione]bisoxindoles".ORGANIC LETTERS 14.2(2012):490-493.