Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution

	Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution
	Xia, Shi Wen ; Lin, Hui ; Chen, Yong Zheng
刊名	CHINESE CHEMICAL LETTERS
	2012
卷号	23 期号:3 页码:289-292
关键词	(R)-2-Chloro-1-(m-chlorophenyl)ethanol LipozymeTL IM Enzymatic transesterification Vinyl acetate Second resolution
ISSN号	1001-8417
通讯作者	Xia, SW (reprint author), Chongqing Univ Posts & Telecommun, Coll Bioinformat, Chongqing 400065, Peoples R China.
产权排序	2
英文摘要	(R)-2-Chloro-1-(m-chlorophenyl)ethanol, a precursor of (R)-3-chlorostyrene oxide which is the key chiral intermediate for the preparation of several beta 3-adrenergic receptor agonists was prepared in 40% yield and 99% ee by the Lipozyme TL IM-catalyzed second resolution of the corresponding racemate in the presence of vinyl acetate. (C) 2012 Shi Wen Xia. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
学科主题	Chemistry
收录类别	SCI
资助信息	National Natural Science Foundation of China [20672110]
语种	英语
WOS记录号	WOS:000301631500010
公开日期	2013-07-03
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23906]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Xia, Shi Wen,Lin, Hui,Chen, Yong Zheng. Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution[J]. CHINESE CHEMICAL LETTERS,2012,23(3):289-292.
APA	Xia, Shi Wen,Lin, Hui,&Chen, Yong Zheng.(2012).Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution.CHINESE CHEMICAL LETTERS,23(3),289-292.
MLA	Xia, Shi Wen,et al."Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution".CHINESE CHEMICAL LETTERS 23.3(2012):289-292.