Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis

	Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis
	He, Dahai ; Ding, Lisheng ; Xu, Hongxi ; Lei, Xinxiang ; Xiao, Hongping ; Zhou, Yan
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2012
卷号	77 期号:19 页码:8435-8443
ISSN号	0022-3263
通讯作者	Xu, HX (reprint author), Shanghai Univ Tradit Chinese Med, Shanghai 201203, Peoples R China.
产权排序	1
英文摘要	Fifteen new lignans, gymnothelignans A-O (1-15), bearing tetrahydrofuran with variable conformations belonging to three potentially related skeletons were isolated from Gymnotheca chinensis Decne. The structures were elucidated by means of detailed spectroscopic analysis. Absolute configurations were assigned using X-ray single-crystal diffraction and chemical transformations. Moreover, by the homology, compounds 1-11 and eupomatilones were confirmed to have uniform R-configuration at C-5. However, a synthesized congener has long been mistaken as 5-epimer of eupomatilone-6. This work provides guidance for the absolute configuration establishment of the subeupomatilone family with trans-H-4 H-5 configuration.
学科主题	Chemistry
收录类别	SCI
资助信息	Chinese Academy of Sciences; National Natural Sciences Foundation of China [30973634, 30900129, 81130069]
语种	英语
WOS记录号	WOS:000313767800007
公开日期	2013-07-03
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23878]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	He, Dahai,Ding, Lisheng,Xu, Hongxi,et al. Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis[J]. JOURNAL OF ORGANIC CHEMISTRY,2012,77(19):8435-8443.
APA	He, Dahai,Ding, Lisheng,Xu, Hongxi,Lei, Xinxiang,Xiao, Hongping,&Zhou, Yan.(2012).Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis.JOURNAL OF ORGANIC CHEMISTRY,77(19),8435-8443.
MLA	He, Dahai,et al."Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis".JOURNAL OF ORGANIC CHEMISTRY 77.19(2012):8435-8443.