DNA based identification of medicinal materials in Chinese patent medicines

	DNA based identification of medicinal materials in Chinese patent medicines
	Chen, Rong ; Dong, Juan ; Cui, Xin ; Wang, Wei ; Yasmeen, Afshan ; Deng, Yun ; Zeng, Xiaomao ; Tang, Zhuo
刊名	SCIENTIFIC REPORTS
	2012
卷号	2 页码:-
ISSN号	2045-2322
通讯作者	Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu, Peoples R China ; Deng, Yun
产权排序	1
英文摘要	Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well refined oral liquids and injections. What's more, this PCR based method can also be developed to an easy to use and cost-effective visual chip by taking advantage of G-quadruplex based Hybridization Chain Reaction. This study demonstrates that DNA identification of specific Medicinal materials is an efficient and cost-effective way to audit highly processed CPM and will assist in monitoring their quality and legality.
学科主题	Science & Technology - Other Topics
收录类别	SCI
资助信息	Chinese Academy of Science (Hundreds of Talents Program); National Sciences Foundation of China [21172215, 21102140]; Innovation Program of the Chinese Academy of Sciences [KSCX2-EW-J-22]; Open Research Fund of State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resource
语种	英语
WOS记录号	WOS:000312274900007
公开日期	2013-07-03
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23871]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Chen, Rong,Dong, Juan,Cui, Xin,et al. DNA based identification of medicinal materials in Chinese patent medicines[J]. SCIENTIFIC REPORTS,2012,2:-.
APA	Chen, Rong.,Dong, Juan.,Cui, Xin.,Wang, Wei.,Yasmeen, Afshan.,...&Tang, Zhuo.(2012).DNA based identification of medicinal materials in Chinese patent medicines.SCIENTIFIC REPORTS,2,-.
MLA	Chen, Rong,et al."DNA based identification of medicinal materials in Chinese patent medicines".SCIENTIFIC REPORTS 2(2012):-.