Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning

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	Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning
	He QL(贺庆利) ; Jiang H(江辉) ; Zhang F(张凤) ; Chen HB(陈海宝) ; Tang GL(唐功利)
刊名	Bioorg. Med. Chem. Lett.
	2008
卷号	18 期号:14 页码:3995-3998
ISSN号	0960-894X
其他题名	Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning
通讯作者	唐功利
英文摘要	Simultaneously isolating more than one receptor of natural product remains a challenge to chemical genetics. Using cyclosporine A as an affinity probe and an optimized phage display cloning procedure, not only cyclophilin A, but also cyclophilin B was isolated as the full-length gene clone from a human brain cDNA library. This optimized protocol can be used to select protein targets of chemicals dependent on the binding affinity rather than on the relative abundance in cells. (c) 2008 Elsevier Ltd. All rights reserved.
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.bmcl.2008.06.006
语种	英语
WOS记录号	WOS:000257640400037
公开日期	2013-06-19
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/25755]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	He QL,Jiang H,Zhang F,et al. Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning[J]. Bioorg. Med. Chem. Lett.,2008,18(14):3995-3998.
APA	贺庆利,江辉,张凤,陈海宝,&唐功利.(2008).Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning.Bioorg. Med. Chem. Lett.,18(14),3995-3998.
MLA	贺庆利,et al."Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning".Bioorg. Med. Chem. Lett. 18.14(2008):3995-3998.